Department of Ophthalmology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, India.
Department of Ophthalmology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, India.
Med Hypotheses. 2018 Dec;121:180-182. doi: 10.1016/j.mehy.2018.10.003. Epub 2018 Oct 6.
Autoimmune thyroiditis (AT) is an important cause of hypothyroidism, and central serous chorioretinopathy (CSCR) is an independent disease of the choroid and retina that leads to accumulation of fluid beneath the retina. While AT has been associated with multiple antibodies, CSCR is still regarded as idiopathic despite extensive research. We hypothesize a causative association between these 2 conditions on the basis of our experience of a case where both CSCR and AT presented simultaneously and depicted a parallel course. CSCR was documented with retinal imaging while AT was documented with serum antibody titers. Further, we discuss the possible mechanisms that may be involved in this intriguing association.
自身免疫性甲状腺炎(AT)是甲状腺功能减退的重要原因,而中心性浆液性脉络膜视网膜病变(CSCR)是一种独立的脉络膜和视网膜疾病,导致视网膜下积液积聚。虽然 AT 与多种抗体有关,但尽管进行了广泛的研究,CSCR 仍被认为是特发性的。根据我们同时出现 CSCR 和 AT 的病例经验,我们假设这两种情况之间存在因果关系,并描述了它们平行的病程。CSCR 通过视网膜成像记录,而 AT 通过血清抗体滴度记录。此外,我们还讨论了可能涉及这种有趣关联的可能机制。