Weant Mallika P, Jesús Caroline Mejías-De, Yerram Prakirthi
Semin Oncol Nurs. 2018 Dec;34(5):501-512. doi: 10.1016/j.soncn.2018.10.011. Epub 2018 Nov 2.
To describe the immunotherapy approaches currently under investigation for the treatment of gliomas. To discuss the management of immune-related adverse effects.
Published literature, clinical trials, and oncology association guidance documents.
There are numerous modalities of immune treatment currently being evaluated in patients with glioma, including peptide vaccines, dendritic cell vaccines, oncolytic viruses, CAR-T cells, and checkpoint inhibitor therapy. Immunotherapy utilizes new mechanisms of treatment that may lead us to the eradication of gliomas.
Immunotherapy is a rapidly growing field in the treatment of gliomas. Oncology nurses are often involved in the safe administration of these therapies, as well as the identification and management of immune-related toxicities.
描述目前正在研究用于治疗胶质瘤的免疫治疗方法。讨论免疫相关不良反应的管理。
已发表的文献、临床试验和肿瘤学协会指导文件。
目前有多种免疫治疗方式正在胶质瘤患者中进行评估，包括肽疫苗、树突状细胞疫苗、溶瘤病毒、嵌合抗原受体T细胞（CAR-T细胞）和检查点抑制剂疗法。免疫疗法利用了新的治疗机制，可能会引领我们根除胶质瘤。
免疫疗法是胶质瘤治疗中一个快速发展的领域。肿瘤学护士经常参与这些疗法的安全给药，以及免疫相关毒性的识别和管理。
