基于量子点的数字均相免疫分析的光谱蓝移的非同步性。
Asynchrony of spectral blue-shifts of quantum dot based digital homogeneous immunoassay.
机构信息
School of Chemistry and Materials Science, Jiangsu Normal University, Shanghai Road 101, Xuzhou, Jiangsu, China.
出版信息
Chem Commun (Camb). 2018 Nov 20;54(93):13103-13106. doi: 10.1039/c8cc06754f.
PMID:30397699
Abstract
A femtomolar digital homogenous immunoassay is developed based on sensitively distinguishing the immunocomplexes labeled with quantum dot (QD) aggregates from the excessive free monodisperse single QDs. The success in quantifying the carcino-embryonic antigen and alpha-fetoprotein in plasma validated the feasibility of our approach for clinical tests.
摘要
基于对量子点（QD）聚集体标记的免疫复合物与过量游离单分散 QD 进行灵敏区分，开发出一种飞摩尔级数字均相免疫分析法。该方法成功定量检测了血浆中的癌胚抗原和甲胎蛋白，验证了我们的方法用于临床检测的可行性。
Zotero 插件