Department of Diagnostic and Interventional Neuroradiology, University Hospital Tuebingen, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.
Department of Neurology with Focus on Neurovascular Diseases and Neurooncology, University Hospital Tuebingen, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.
Clin Neuroradiol. 2020 Mar;30(1):101-107. doi: 10.1007/s00062-018-0740-y. Epub 2018 Nov 5.
To evaluate the potential benefit in image quality of the iterative reconstruction (IR) technique advanced modelled iterative reconstruction (ADMIRE) in CT angiography (CTA) of supra-aortic arteries compared to sinogram affirmed iterative reconstruction (SAFIRE) and standard filtered back projection (FBP) in one patients' group.
In this study 29 patients underwent standard CTA of supra-aortic arteries. Images were reconstructed using three different reconstruction algorithms, FBP, and IR techniques ADMIRE and SAFIRE. General image quality was assessed by two radiologists in different arterial segments using a 5-point Likert scale. Mean attenuation and noise were measured at different levels of each vessel and signal-to-noise ratio (SNR) was calculated. Interrater variability was determined.
Regarding total image quality IR showed only excellent, very good and good results and was more often graded excellent and very good than FBP reconstruction. Image noise levels and SNR were significantly (p < 0.01) improved in IR at the bilateral subclavian arteries (only in SAFIRE), vertebral V1 and V3 segments, common carotid arteries and proximal and distal internal carotid arteries. No significant differences in image quality were found when comparing SAFIRE and ADMIRE reconstructions except for V1 and V3. In these regions ADMIRE showed significantly better image quality than SAFIRE (p < 0.001 and p < 0.01). Interrater agreement was almost perfect (κ = 0.88) for different image quality parameters.
The CTA of supra-aortic arteries using the IR techniques SAFIRE and ADMIRE was superior to FBP when comparing the objective and subjective image quality and ADMIRE has the potential to overcome SAFIRE.
评估迭代重建（IR）技术高级模型迭代重建（ADMIRE）在主动脉以上动脉 CT 血管造影（CTA）中相对于正弦图确认迭代重建（SAFIRE）和标准滤波反投影（FBP）的潜在图像质量优势，在一组患者中进行。
本研究对 29 例主动脉以上动脉行标准 CTA。使用三种不同的重建算法，即 FBP 和 IR 技术 ADMIRE 和 SAFIRE，对图像进行重建。两位放射科医生在不同的动脉节段使用 5 分 Likert 量表评估总体图像质量。在每个血管的不同水平测量平均衰减和噪声，并计算信噪比（SNR）。确定组内变异。
在总图像质量方面，IR 仅显示出极好、很好和良好的结果，并且比 FBP 重建更常被评为极好和很好。在双侧锁骨下动脉（仅在 SAFIRE 中）、椎动脉 V1 和 V3 段、颈总动脉和颈内动脉近端和远端，IR 可显著（p<0.01）降低图像噪声水平和 SNR。比较 SAFIRE 和 ADMIRE 重建时，除了 V1 和 V3 外，图像质量没有显著差异。在这些区域，ADMIRE 显示出明显优于 SAFIRE 的图像质量（p<0.001 和 p<0.01）。不同图像质量参数的组内一致性几乎为完美（κ=0.88）。
与 FBP 相比，在比较客观和主观图像质量时，主动脉以上动脉的 CTA 使用 IR 技术 SAFIRE 和 ADMIRE 具有优势，ADMIRE 有潜力克服 SAFIRE。
