School of Chemistry, University of Bristol, Bristol, BS8 1TS, UK.
Angew Chem Int Ed Engl. 2019 Jan 2;58(1):221-225. doi: 10.1002/anie.201811460. Epub 2018 Nov 29.
Rh-catalyzed carbonylative C-C bond activation of cyclopropylamides generates configurationally stable rhodacyclopentanones that engage tethered alkenes in (3+1+2) cycloadditions. These studies provide the first examples of multicomponent cycloadditions that proceed through C-C bond activation of "simple" electron poor cyclopropanes.
铑催化的环丙酰胺羰基化 C-C 键活化生成构型稳定的铑环戊酮，这些环戊酮与连接的烯烃进行（3+1+2）环加成反应。这些研究提供了首例通过“简单”缺电子环丙烷的 C-C 键活化进行的多组分环加成反应的实例。
