Pernot Carina C E G, Zwiers Ineke, Ten Cate-Hoek Arina J, Wittens Cees H A
Department of Surgery, Maastricht University Medical Centre, Maastricht, the Netherlands. Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, the Netherlands.
Department of Surgery, Maastricht University Medical Centre, Maastricht, the Netherlands.
J Wound Care. 2018 Nov 2;27(11):758-763. doi: 10.12968/jowc.2018.27.11.758.
To explore the need for an extended diagnostic workup in patients with venous leg ulcers (VLUs) and to establish the prevalence of the underlying causes of VLU.
This retrospective cohort study analysed data from patients with VLU. The visual analogue scale (VAS) was used for pain assessment. The ankle-brachial index (ABI) was measured to exclude patients with arterial pathology. A duplex was performed. All patients received a wound treatment plan and ambulatory compression therapy. Continuous variables were presented as mean±standard deviation (SD) or median and interquartile range (IQR). Mann-Whitney U test and Kruskal-Wallis were used. When normally distributed, an independent sample t-test was used.
A total of 70 patients were recruited. Of these, 18 (25.7%) experienced a VLU once and 52 (74.3%) had a recurrent VLU. Treatment of the underlying lesions was performed in almost 30% of patients. Patients who were treated showed almost two times slower healing rates compared with those who were not treated for an underlying pathology. The mean time in patient referral exceeded two years, and patients who did not see their GP were treated by nurses who did not provide regular feedback the GP; as a result, compression therapy was not always adequate.
Patients with a VLU showing no signs of healing after 2 months should be referred to a dedicated wound care centre to avoid delays.
探讨下肢静脉溃疡(VLU)患者进行扩展诊断检查的必要性,并确定VLU潜在病因的患病率。
这项回顾性队列研究分析了VLU患者的数据。采用视觉模拟量表(VAS)进行疼痛评估。测量踝臂指数(ABI)以排除有动脉病变的患者。进行了双功超声检查。所有患者均接受了伤口治疗计划和门诊压迫治疗。连续变量以均值±标准差(SD)或中位数和四分位间距(IQR)表示。使用曼-惠特尼U检验和克鲁斯卡尔-沃利斯检验。当数据呈正态分布时,使用独立样本t检验。
共招募了70名患者。其中,18名(25.7%)曾患过一次VLU,52名(74.3%)有复发性VLU。近30%的患者接受了潜在病变的治疗。接受治疗的患者愈合速度比未接受潜在病变治疗的患者慢近两倍。患者转诊的平均时间超过两年,未看全科医生(GP)的患者由护士治疗,护士未向GP提供定期反馈;因此,压迫治疗并不总是足够的。
VLU患者在2个月后无愈合迹象应转诊至专门的伤口护理中心以避免延误。