Kats V A, Volchenko N N
Arkh Patol. 1987;49(5):47-52.
Histology and ultrastructure of human granular cell tumors (GCT) are studied. Apart from "granular" cells which are the main component of the tumor, GCT contain the cells of ordinary structure with signs of neurogenic differentiation, cell processus typical for the nervous tissue and peripheral nervous tissue tumors (these processus are in a close space connection with "granular" cells) as well as structurally transitional cells. This implies that "granular" cells are likely to originate from the ordinary lemmocytes as a result of disturbance and hypertrophy of intracellular processus. Preoperative diagnosis of this rare peculiar neurogenic tumor is difficult and the diagnosis is possible only after the operative material examination. If other signs of malignancy are lacking, infiltrative growth typical for these tumors allows one to consider them locally-destructive neoplasms.
对人类颗粒细胞瘤（GCT）的组织学和超微结构进行了研究。除了作为肿瘤主要成分的“颗粒”细胞外，颗粒细胞瘤还包含具有神经源性分化迹象的普通结构细胞、神经组织和周围神经组织肿瘤典型的细胞突起（这些突起与“颗粒”细胞在紧密的空间连接中）以及结构过渡细胞。这意味着“颗粒”细胞可能是由于细胞突起的紊乱和肥大而从普通的雪旺细胞起源的。这种罕见的特殊神经源性肿瘤的术前诊断很困难，只有在对手术材料进行检查后才能做出诊断。如果缺乏其他恶性迹象，这些肿瘤典型的浸润性生长使其可被视为局部破坏性肿瘤。
