[Changes in the segmental flexibility and conformation stability of side groups in spin-labeled molecules of 2 IgG subclasses in the serum of normal cows and cows in various pathological states].

The segmental flexibility of molecules from two IgG subclasses of cows' blood serum was first observed. It was shown that IgG1 molecule has a more flexible hinge region than IgG2 molecule and lower local conformational stability. At the same time the states of IgG1 and IgG2 molecules determined by dynamic-steric characteristics for ill and healthy cows practically did not differ.