Onalan Emine, Andsoy Isil I, Ersoy Omer F
J Perianesth Nurs. 2019 Jun;34(3):539-550. doi: 10.1016/j.jopan.2018.07.007. Epub 2018 Nov 3.
The aim of this study was to evaluate the effect of preoperative oral carbohydrate solution (OCS) administration on postoperative insulin resistance and patient comfort in elective laparoscopic cholecystectomy.
Randomized controlled clinical study.
The experimental group received OCS. The control group did not eat or drink before surgery. Glucose and insulin level were measured at baseline, 2 hours before surgery, and at the first and third hour after surgery. Insulin resistance was assessed by the homeostasis model assessment of insulin resistance (HOMA-IR). The visual analogue scale (VAS) and general comfort scale (GCS) were used to assess postoperative comfort level.
A significant increase in the glucose level was observed in both groups (P < 0.05). A change in glucose level was significantly higher in the control group (P = .014). HOMA-IR values did not change significantly in the OCS group (P = .160). In the OCS group VAS scores were significantly lower (P < .0001). The OCS group had significantly higher relief (P = .014), ease (P = .001), and transcendence (P < .0001) scores.
OCS decreases insulin resistance and increases comfort.
本研究旨在评估择期腹腔镜胆囊切除术前口服碳水化合物溶液（OCS）对术后胰岛素抵抗及患者舒适度的影响。
随机对照临床研究。
实验组接受OCS。对照组术前禁食禁水。在基线、术前2小时、术后第1小时和第3小时测量血糖和胰岛素水平。采用胰岛素抵抗稳态模型评估（HOMA-IR）评估胰岛素抵抗。使用视觉模拟评分法（VAS）和总体舒适度量表（GCS）评估术后舒适度。
两组血糖水平均显著升高（P < 0.05）。对照组血糖水平变化显著更高（P = 0.014）。OCS组HOMA-IR值无显著变化（P = 0.160）。OCS组VAS评分显著更低（P < 0.0001）。OCS组在缓解（P = 0.014）、轻松（P = 0.001）和超越（P < 0.0001）方面得分显著更高。
OCS可降低胰岛素抵抗并提高舒适度。
