Suppr超能文献

肿瘤学中的图像引导骨愈合

Image-Guided Bone Consolidation in Oncology.

作者信息

Buy Xavier, Catena Vittorio, Roubaud Guilhem, Crombe Amandine, Kind Michèle, Palussiere Jean

机构信息

Department of Radiology, Institut Bergonie, Bordeaux, France.

Department of Medical Oncology, Institut Bergonie, Bordeaux, France.

出版信息

Semin Intervent Radiol. 2018 Oct;35(4):221-228. doi: 10.1055/s-0038-1669468. Epub 2018 Nov 5.

Abstract

Occurrence of bone metastases is a common event in oncology. Bone metastases are associated with pain, functional impairment, and fractures, particularly when weight-bearing bones are involved. Management of bone metastases has been improved by the development of various interventional radiology consolidation techniques. Cementoplasty is based on injection of acrylic cement into a weakened bone to reinforce it and to control pain. This minimally invasive technique has proven its efficacy for flat bone submitted to compression forces. However, resistance to torsion forces is limited and, thus, treatment of long bones should be considered with caution. In recent years, variant techniques of percutaneous bone consolidation have emerged, including expansion devices for vertebral augmentation and percutaneous screw fixation for pelvic bone and proximal femur tumors. Research projects are ongoing to develop drug-loaded cements to use them as therapeutic vectors. However, release of drugs is still poorly controlled and conventional polymethylmethacrylate cement remains the gold standard in oncology. Image-guided consolidation techniques enhance the array of treatments in bone oncology. Multidisciplinary approach is mandatory to select the best indications.

摘要

骨转移的发生在肿瘤学中是常见事件。骨转移与疼痛、功能障碍和骨折相关,尤其是当负重骨受累时。各种介入放射学强化技术的发展改善了骨转移的治疗。骨水泥成形术是将丙烯酸骨水泥注入弱化骨以加固并控制疼痛。这种微创技术已证明其对承受压缩力的扁平骨有效。然而,其抗扭力有限,因此,治疗长骨时应谨慎考虑。近年来,出现了经皮骨强化的变体技术,包括用于椎体强化的扩张装置以及用于骨盆骨和股骨近端肿瘤的经皮螺钉固定。正在开展研究项目以开发载药骨水泥用作治疗载体。然而,药物释放仍难以控制,传统的聚甲基丙烯酸甲酯骨水泥仍是肿瘤学中的金标准。图像引导的强化技术增加了骨肿瘤学的治疗手段。必须采用多学科方法来选择最佳适应证。

相似文献

1
Image-Guided Bone Consolidation in Oncology.
Semin Intervent Radiol. 2018 Oct;35(4):221-228. doi: 10.1055/s-0038-1669468. Epub 2018 Nov 5.
2
[Image-guided bone consolidation in oncology: Cementoplasty and percutaneous screw fixation].
Bull Cancer. 2017 May;104(5):423-432. doi: 10.1016/j.bulcan.2016.12.009. Epub 2017 Mar 18.
4
Interventional radiology for treatment of bone metastases.
Cancer Radiother. 2020 Aug;24(5):374-378. doi: 10.1016/j.canrad.2020.04.006. Epub 2020 Jun 8.
5
Vertebroplasty and vertebral augmentation techniques.
Tech Vasc Interv Radiol. 2009 Mar;12(1):44-50. doi: 10.1053/j.tvir.2009.06.005.
6
Percutaneous Fixation by Internal Cemented Screw for the Treatment of Unstable Osseous Disease in Cancer Patients.
Semin Intervent Radiol. 2018 Oct;35(4):238-247. doi: 10.1055/s-0038-1673359. Epub 2018 Nov 5.
8
Percutaneous osteosynthesis in the pelvis in cancer patients.
Eur Radiol. 2016 Jun;26(6):1631-9. doi: 10.1007/s00330-015-3971-1. Epub 2015 Aug 30.
9
[Combined bipolar radiofrequency and cementoplasty of bone metastases].
J Radiol. 2007 Sep;88(9 Pt 2):1242-7. doi: 10.1016/s0221-0363(07)91333-5.
10
Interventional radiology in bone metastases.
Eur J Cancer Care (Engl). 2017 Nov;26(6). doi: 10.1111/ecc.12741. Epub 2017 Sep 5.

引用本文的文献

1
Minimally invasive interventional guided imaging therapies of musculoskeletal tumors.
Quant Imaging Med Surg. 2024 Nov 1;14(11):7908-7936. doi: 10.21037/qims-24-452. Epub 2024 Oct 14.
2
Percutaneous Vertebral Augmentation and Thermal Ablation in Patients with Spinal Metastases.
Semin Intervent Radiol. 2024 Jul 10;41(2):170-175. doi: 10.1055/s-0044-1787166. eCollection 2024 Apr.
3
O-arm-guided percutaneous microwave ablation and cementoplasty for the treatment of pelvic acetabulum bone metastasis.
Front Surg. 2022 Sep 12;9:929044. doi: 10.3389/fsurg.2022.929044. eCollection 2022.
4
Interventional Palliation of Painful Extraspinal Musculoskeletal Metastases.
Semin Intervent Radiol. 2022 Jun 30;39(2):176-183. doi: 10.1055/s-0042-1745787. eCollection 2022 Apr.

本文引用的文献

1
Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases.
Sci Rep. 2017 Aug 3;7(1):7196. doi: 10.1038/s41598-017-07649-z.
2
Safety and efficacy of multilevel vertebroplasty for painful osteolytic spinal metastases: a single-centre experience.
Eur Radiol. 2017 Aug;27(8):3436-3442. doi: 10.1007/s00330-016-4683-x. Epub 2016 Dec 14.
3
Image-Guided Spinal Ablation: A Review.
Cardiovasc Intervent Radiol. 2016 Sep;39(9):1229-38. doi: 10.1007/s00270-016-1402-6. Epub 2016 Jun 21.
5
[Bone metastases relapse after cementoplasty: Case report and discussion about the combination of radiotherapy and cementoplasty].
Cancer Radiother. 2016 Apr;20(2):109-14. doi: 10.1016/j.canrad.2015.09.012. Epub 2016 Mar 2.
6
Percutaneous osteosynthesis in the pelvis in cancer patients.
Eur Radiol. 2016 Jun;26(6):1631-9. doi: 10.1007/s00330-015-3971-1. Epub 2015 Aug 30.
7
8
Impending fracture: A difficult diagnosis.
Injury. 2014 Dec;45 Suppl 6:S138-41. doi: 10.1016/j.injury.2014.10.038. Epub 2014 Nov 4.
9
Percutaneous long bone cementoplasty of the limbs: experience with fifty-one non-surgical patients.
Eur Radiol. 2014 Dec;24(12):3059-68. doi: 10.1007/s00330-014-3357-9. Epub 2014 Aug 6.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验