Xie Lixiang, Liu Zhongxiao, Zhang Xiuli, Xu Kai, Xu Qian, Lu Li, Hu Chunfeng, Han Shuguang, Li Jingjing
Department of Radiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002, P.R. China.
Exp Ther Med. 2018 Nov;16(5):4260-4264. doi: 10.3892/etm.2018.6717. Epub 2018 Sep 11.
The aim of the current study was to investigate the atrial septal aneurysm (ASA) incidence rate and describe its morphologic features by dual-source computed tomography (DSCT). A total of 8,626 patients (4,284 men and 4,342 women) who underwent DSCT examinations were enrolled. The presence of ASA was defined as the protrusion of the complete or partial interatrial septum with a maximum vertical distance (MVD) from the atrial septum plane of >10 mm during a cardiac cycle and a diameter of the aneurysm base of >15 mm. The MVD and direction of the protrusion, as well as other abnormalities, were recorded. The ASA patients were classified by both gender and directions of protrusion into four groups, including the right atrium (RA) and left atrium (LA) groups in males and females, respectively. Values across groups were compared using the independent-sample t-test and differences in qualitative variables were assessed with the χ test. Of the 8,626 patients, 51 (0.6%) were diagnosed with ASA (mean age, 62±10 years), including 23 (0.5%) males and 28 (0.6%) females. There were no significant differences in the age (t=-1.37, P>0.05) and incidence rate (χ=0.43, P>0.05) between the male and female groups. However, there were significant differences in the mean ages (t=-2.20, P<0.05) and the gender proportions (χ=7.39, P<0.05) of patients in the RA and LA groups. In the two male groups, no significant differences were observed in the diameters of the ASA bases and MVD in the RA and LA groups. In the female groups, the differences in the MVD of protrusion in RA and LA groups were non-significant, whereas the diameters of the base of ASA demonstrated significant differences (t=2.27, P<0.05). In conclusion, the ASA incidence rate was 0.6%, and electrocardiography-gated DSCT scan served as an alternative diagnostic technique for the detection of ASA. It is essential for radiologists to recognize this clinical entity and to minimize misdiagnoses and missed diagnoses.
本研究的目的是通过双源计算机断层扫描（DSCT）调查房间隔瘤（ASA）的发病率，并描述其形态学特征。共有8626例接受DSCT检查的患者（4284例男性和4342例女性）纳入研究。ASA的存在定义为在心动周期中，完整或部分房间隔突出，距房间隔平面的最大垂直距离（MVD）>10mm，且瘤体基部直径>15mm。记录MVD、突出方向以及其他异常情况。ASA患者按性别和突出方向分为四组，分别为男性和女性的右心房（RA）组和左心房（LA）组。使用独立样本t检验比较各组间数值，用χ检验评估定性变量的差异。在8626例患者中，51例（0.6%）被诊断为ASA（平均年龄62±10岁），其中男性23例（0.5%），女性28例（0.6%）。男女组之间在年龄（t=-1.37，P>0.05）和发病率（χ=0.43，P>0.05）方面无显著差异。然而，RA组和LA组患者的平均年龄（t=-2.20，P<0.05）和性别比例（χ=7.39，P<0.05）存在显著差异。在两个男性组中，RA组和LA组的ASA基部直径和MVD无显著差异。在女性组中，RA组和LA组突出的MVD差异不显著，而ASA基部直径显示出显著差异（t=2.27，P<0.
