Kurzawski Jacek, Janion Marianna, Sielski Janusz
Department of Cardiology, Swietokrzyskie Centrum Kardiologii, Grunwaldzka 45, 25-736 Kielce, Poland.
Echocardiography. 2007 Oct;24(9):895-900. doi: 10.1111/j.1540-8175.2007.00500.x.
Atrial septal aneurysm (ASA) is a rare heart defect regarded as a source of arterial emboli. The main objective of the study was to assess the role of ASA morphology in the etiology of embolism.
Eighty-eight subjects were included after transthoracic echocardiography positive for ASA. Medical history of embolic events was obtained in 13 patients (14.8%). Magnitude, location, size of aneurysm, oscillation, direction of bulging, the presence of interatrial shunt and source of any potential cardiac embolus material were assessed, and the size of the left atrium, the area of both atria, and the presence of any valve prolapse syndrome were recorded. The occurrence of atrial fibrillation or flutter and the presence of concomitant diseases and other clinical features were also estimated.
The occurrence of arterial emboli was not related to ASA morphology. Coexisting diseases, smoking and left atrial dimension were significantly correlated with the occurrence of arterial emboli.
Ischemic events were not significantly correlated with the ASA presence. The present findings suggest other causes of vascular events in patients with ASA.
房间隔瘤（ASA）是一种罕见的心脏缺陷，被视为动脉栓子的来源。本研究的主要目的是评估ASA形态在栓塞病因中的作用。
经胸超声心动图检查ASA呈阳性的88名受试者被纳入研究。13名患者（14.8%）有栓塞事件病史。评估动脉瘤的大小、位置、尺寸、摆动、膨出方向、房间隔分流的存在以及任何潜在心脏栓子物质的来源，并记录左心房大小、双心房面积以及任何瓣膜脱垂综合征的存在情况。还评估了心房颤动或扑动的发生情况以及并存疾病和其他临床特征。
动脉栓塞的发生与ASA形态无关。并存疾病、吸烟和左心房大小与动脉栓塞的发生显著相关。
缺血事件与ASA的存在无显著相关性。目前的研究结果提示ASA患者血管事件有其他病因。
