Arribillaga Leandro, Ledesma Marta, Montedoro Ariel, Pisano Florencia, Bengió Rubén Guillermo, Oulton Guillermo, Grutadauria Gracia, Bengió Ruben Hugo
Centro Urológico Profesor Bengió Córdoba. Córdoba. Argentina.
Arch Esp Urol. 2018 Nov;71(9):752-756.
To evaluate if there is a correlation between the abdominal leak pressure point (ALPP) of the urodynamic study and several tools to evaluate severity and quality of life associated to stress urine incontinence (SUI).
Prospective correlation study of women referred to urodynamic study for stress urinary incontinence in Centro Urológico Profesor Bengió between September 2014 and October 2015. Anamnesis, physical examination (where the SUI was demonstrated), ICIQSF urine incontinence questionnaire and incontinence impact questionnaire (IIQ-7) were performed to every patient. Uroflowmetry and complete urodynamic study were performed in all cases. Intrinsic sphincter deficiency (ISD) was defined as ALPP value ≤ 60 cm H2O. The relation between abdominal leak pressure point (ALPP) and incontinence severity measurements and quality of life (daily protectors, Sandvik score, ISIQ-SF score and short IIQ7 score) was evaluated with the Spearman coefficient correlation.
105 females were studied. Mean ALPP was 84 H2O cm (30-170). 21 and 84 patients had ALPP values lower and higher than 60 H2O cm respectively. There were no differences between the groups when general and demographic characteristics were evaluated. No correlation between ALPP and incontinence severity measurements was demonstrated: daily protectors (ρ 0.10; p NS), Sandvik severity score (ρ 0.05; p NS), ISIQ-SF score (ρ 0.0004; p NS) and IIQ7 Score (ρ 0.06; p NS). When patients with IED (ALPP ≤ 60 cm H2O) and those without IED DEI (ALPP > 60 cm H2O) were analyzed, there was no statistically significant difference between the groups in the comparison according to severity and quality of life questionnaires.
In this series, there is not a significant correlation between abdominal leak pressure point and severity and quality of life measurements in patients with stress urinary incontinence.
评估尿动力学研究中的腹部漏尿点压力（ALPP）与几种用于评估压力性尿失禁（SUI）严重程度及生活质量的工具之间是否存在相关性。
对2014年9月至2015年10月间在Centro Urológico Profesor Bengió因压力性尿失禁接受尿动力学研究的女性进行前瞻性相关性研究。对每位患者进行了病史采集、体格检查（证实存在SUI）、ICIQ-SF尿失禁问卷及尿失禁影响问卷（IIQ-7）。所有病例均进行了尿流率测定及完整的尿动力学研究。内在括约肌缺陷（ISD）定义为ALPP值≤60 cm H₂O。采用Spearman系数相关性评估腹部漏尿点压力（ALPP）与尿失禁严重程度测量指标及生活质量（日常护垫使用情况、Sandvik评分、ISIQ-SF评分及简短IIQ7评分）之间的关系。
共研究了105名女性。平均ALPP为84 H₂O cm（30 - 170）。分别有21例和84例患者的ALPP值低于和高于60 H₂O cm。在评估一般和人口统计学特征时，两组之间无差异。未显示ALPP与尿失禁严重程度测量指标之间存在相关性：日常护垫使用情况（ρ 0.10；p无统计学意义）、Sandvik严重程度评分（ρ 0.05；p无统计学意义）、ISIQ-SF评分（ρ 0.0004；p无统计学意义）及IIQ7评分（ρ 0.06；p无统计学意义）。当分析存在内在括约肌缺陷（ALPP≤60 cm H₂O）和不存在内在括约肌缺陷（ALPP>6cm H₂O）的患者时，根据严重程度和生活质量问卷进行的组间比较无统计学显著差异。
在本系列研究中，压力性尿失禁患者的腹部漏尿点压力与严重程度及生活质量测量指标之间无显著相关性。
