Grimes Cara L, Hanissian Paul D, Strohbehn Kris, Goldman Marlene B, Whiteside James L
Department of Gynecology and Obstetrics, Johns Hopkins Hospital, Baltimore, Maryland, USA.
Int J Gynaecol Obstet. 2008 Aug;102(2):120-3. doi: 10.1016/j.ijgo.2008.04.004. Epub 2008 May 27.
To evaluate preoperative abdominal leak point pressures (ALPP) with pre- and postoperative Incontinence Severity Index (ISI) scores.
A review of women who underwent a midurethral sling procedure between August 2004 and April 2006 was conducted. Eligible women completed preoperative urodynamic testing with ALPP determination and subjective incontinence severity assessment using the ISI before and 6 weeks after surgery. The ISI and ALPP relationship was analyzed using a Spearman rank correlation (Rho).
Ninety-nine women met the inclusion criteria. Mean ALPP was 77.7 (25-172 cm H2O). Mean improvement in ISI following surgery was 4 (-8 to 12). ALPP correlated with preoperative ISI (Spearman Rho -0.28, P=0.01), preoperative leakage frequency (ISI question 1) (Spearman Rho -0.32, P=0.001), and the ISI change 6 weeks postoperatively (ISI-delta) (Spearman Rho -0.23, P=0.002).
ALPP is associated with subjective incontinence severity. Women with the lowest ALPP improved most following a midurethral sling procedure.
通过术前和术后尿失禁严重程度指数（ISI）评分评估术前腹部漏尿点压力（ALPP）。
对2004年8月至2006年4月间接受中段尿道吊带手术的女性进行回顾性研究。符合条件的女性在术前进行尿动力学检测以测定ALPP，并在手术前及术后6周使用ISI进行主观尿失禁严重程度评估。使用Spearman等级相关性（Rho）分析ISI与ALPP之间的关系。
99名女性符合纳入标准。平均ALPP为77.7（25 - 172 cm H2O）。术后ISI的平均改善值为4（-8至12）。ALPP与术前ISI（Spearman Rho -0.28，P = 0.01）、术前漏尿频率（ISI问题1）（Spearman Rho -0.32，P = 0.001）以及术后6周的ISI变化（ISI - 差值）（Spearman Rho -0.23，P = 0.002）相关。
ALPP与主观尿失禁严重程度相关。ALPP最低的女性在中段尿道吊带手术后改善最为明显。
