Department of Materials Science and Engineering , Johns Hopkins University , Baltimore , Maryland 21218 , United States.
State Key Laboratory of Electronic Thin Films and Integrated Devices, School of Optoelectronic Information , University of Electronic Science and Technology of China , Chengdu 610054 , People's Republic of China.
Chem Rev. 2019 Jan 9;119(1):3-35. doi: 10.1021/acs.chemrev.8b00016. Epub 2018 Nov 7.
The strong and controllable chemical sensitivity of organic semiconductors (OSCs) and the amplification capability of transistors in circuits make use of OSC-based field-effect transistors compelling for chemical sensors. Analytes detected and assayed range from few-atom gas-phase molecules that may have adverse health and security implications to biomacromolecules (proteins, nucleic acids) that may be markers for physiological processes and medical conditions. This review highlights recent progress in organic field-effect transistor (OFET) chemical sensors, emphasizing advances from the past 5 years and including aspects of OSC morphology and the role of adjacent dielectrics. Design elements of the OSCs and various formats for the devices are illustrated and evaluated. Challenges associated with the present state of the art and future opportunities are also discussed.
有机半导体（OSC）具有较强的化学敏感性和可控性，以及晶体管在电路中的放大能力，这使得基于 OSC 的场效应晶体管在化学传感器方面具有吸引力。被检测和分析的分析物范围从可能对健康和安全有不利影响的少数原子气相分子到可能是生理过程和医疗状况标志物的生物大分子（蛋白质、核酸）。这篇综述强调了过去 5 年来的进展，突出了有机场效应晶体管（OFET）化学传感器的最新进展，包括 OSC 形态和相邻电介质的作用等方面。本文还阐述和评估了 OSCs 的设计要素以及各种器件结构。此外，还讨论了当前技术的挑战和未来的机遇。
