1 Department of Radiology, University of Illinois College of Medicine, 1740 W Taylor St, Rm. 2483 (MC 931), Chicago, IL 60612.
2 Loyola University Health System, Maywood, IL.
AJR Am J Roentgenol. 2019 Jan;212(1):157-165. doi: 10.2214/AJR.18.19991. Epub 2018 Nov 7.
Voriconazole is an antifungal medication used primarily for the treatment of Candida and Aspergillus infections. A fairly newly described side effect of long-term voriconazole use is periostitis. The purpose of this article is to describe the main differential consideration-hypertrophic osteoarthropathy-and other differential diagnoses, including venous stasis, thyroid acropachy, and hypervitaminosis A.
With knowledge of imaging appearance, clinical manifestations, and outcomes, radiologists can make an accurate diagnosis of voriconazole-induced periostitis, and clinical teams can initiate appropriate management.
伏立康唑是一种抗真菌药物，主要用于治疗念珠菌和曲霉菌感染。长期使用伏立康唑后出现的一种新的副作用是骨膜炎。本文旨在描述主要的鉴别诊断考虑因素——肥大性骨关节病，以及其他鉴别诊断，包括静脉淤滞、甲状腺肢端病和维生素 A 过多症。
放射科医生通过了解影像学表现、临床表现和结果，可以准确诊断伏立康唑引起的骨膜炎，临床团队可以采取适当的治疗方法。
