• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Managing Clonal Hematopoiesis in Patients With Solid Tumors.实体瘤患者克隆性造血的管理
J Clin Oncol. 2019 Jan 1;37(1):7-11. doi: 10.1200/JCO.18.00331. Epub 2018 Nov 7.
2
Clonal hematopoiesis: Pre-cancer PLUS.克隆性造血：癌前 PLUS。
Adv Cancer Res. 2019;141:85-128. doi: 10.1016/bs.acr.2018.12.003. Epub 2019 Jan 14.
3
Inflammatory cytokines promote clonal hematopoiesis with specific mutations in ulcerative colitis patients.炎症细胞因子促进溃疡性结肠炎患者具有特定突变的克隆性造血。
Exp Hematol. 2019 Dec;80:36-41.e3. doi: 10.1016/j.exphem.2019.11.008. Epub 2019 Dec 5.
4
Clonal Hematopoiesis Confers Predisposition to Both Cardiovascular Disease and Cancer: A Newly Recognized Link Between Two Major Killers.克隆性造血既增加心血管疾病风险，也增加患癌风险：两大主要致死病因之间新发现的关联
Ann Intern Med. 2018 Jul 17;169(2):116-117. doi: 10.7326/M18-0737. Epub 2018 May 29.
5
Clonal hematopoiesis as a model for premalignant changes during aging.克隆性造血作为衰老过程中癌前变化的模型。
Exp Hematol. 2020 Mar;83:48-56. doi: 10.1016/j.exphem.2019.12.001. Epub 2019 Dec 12.
6
Identification of Clonal Hematopoiesis Mutations in Solid Tumor Patients Undergoing Unpaired Next-Generation Sequencing Assays.实体瘤患者在接受非配对下一代测序检测时的克隆性造血基因突变的鉴定。
Clin Cancer Res. 2018 Dec 1;24(23):5918-5924. doi: 10.1158/1078-0432.CCR-18-1201. Epub 2018 Jun 4.
7
The Clinical Management of Clonal Hematopoiesis: Creation of a Clonal Hematopoiesis Clinic.克隆性造血的临床管理：克隆性造血临床的建立。
Hematol Oncol Clin North Am. 2020 Apr;34(2):357-367. doi: 10.1016/j.hoc.2019.11.006. Epub 2020 Jan 18.
8
[Clonal Hematopoiesis and Solid Cancer].[克隆性造血与实体癌]
Gan To Kagaku Ryoho. 2023 Feb;50(2):129-133.
9
Clonal hematopoiesis in human aging and disease.人类衰老和疾病中的克隆性造血
Science. 2019 Nov 1;366(6465). doi: 10.1126/science.aan4673.
10
Targeted, Amplicon-Based, Next-Generation Sequencing to Detect Age-Related Clonal Hematopoiesis.基于靶向扩增子的新一代测序技术检测与年龄相关的克隆性造血
Methods Mol Biol. 2019;2045:167-180. doi: 10.1007/7651_2019_216.

引用本文的文献

1
Detection of human brain cancers using genomic and immune cell characterization of cerebrospinal fluid through CSF-BAM.通过脑脊液 - BAM对脑脊液进行基因组和免疫细胞特征分析以检测人脑癌。
Cancer Discov. 2025 Aug 25. doi: 10.1158/2159-8290.CD-24-1788.
2
Ageing, immune fitness and cancer.衰老、免疫健康与癌症。
Nat Rev Cancer. 2025 Aug 14. doi: 10.1038/s41568-025-00858-z.
3
Fragmentomic-based algorithm to computationally predict tumor-somatic, germline, and clonal hematopoiesis variant origin in liquid biopsy.基于片段组学的算法，用于在液体活检中通过计算预测肿瘤体细胞、种系和克隆性造血变异起源。
J Liq Biopsy. 2025 Jul 11;9:100311. doi: 10.1016/j.jlb.2025.100311. eCollection 2025 Sep.
4
Clonal hematopoiesis in myeloid malignancies and solid tumors.髓系恶性肿瘤和实体瘤中的克隆性造血
Nat Cancer. 2025 Jul 18. doi: 10.1038/s43018-025-01014-0.
5
Clinical Significance of TP53-Mutant Clonal Hematopoiesis Across Diseases.跨疾病的TP53突变克隆性造血的临床意义
Blood Cancer Discov. 2025 Jul 1;6(4):298-306. doi: 10.1158/2643-3230.BCD-24-0355.
6
Heart Failure Post-Hematopoietic Cell Transplantation in Patients With Lymphoma: Another Piece of the CHIP Puzzle.淋巴瘤患者造血细胞移植后的心力衰竭：CHIP难题的另一块拼图
JACC CardioOncol. 2025 Jan 21;7(1):34-37. doi: 10.1016/j.jaccao.2024.12.001. eCollection 2025 Jan.
7
Genomic ascertainment to quantify prevalence and cancer risk in adults with pathogenic and likely pathogenic germline variants in RASopathy genes.基因组确定以量化患有RAS病基因中致病和可能致病种系变异的成年人的患病率和癌症风险。
medRxiv. 2024 Oct 11:2024.10.09.24314324. doi: 10.1101/2024.10.09.24314324.
8
Impact of cytotoxic therapy on clonal hematopoiesis and myeloid neoplasms in breast cancer patients.细胞毒疗法对乳腺癌患者克隆性造血和髓系肿瘤的影响。
Medicine (Baltimore). 2024 Nov 15;103(46):e40540. doi: 10.1097/MD.0000000000040540.
9
A View of Myeloid Transformation through the Hallmarks of Cancer.从癌症的特征看骨髓转化。
Blood Cancer Discov. 2024 Nov 1;5(6):377-387. doi: 10.1158/2643-3230.BCD-24-0009.
10
Distinct landscape and clinical implications of therapy-related clonal hematopoiesis.治疗相关的克隆性造血的独特景观和临床意义。
J Clin Invest. 2024 Oct 1;134(19):e180069. doi: 10.1172/JCI180069.

本文引用的文献

1
Prevalence of Clonal Hematopoiesis Mutations in Tumor-Only Clinical Genomic Profiling of Solid Tumors.实体瘤肿瘤特异性临床基因组分析中克隆性造血基因突变的发生率。
JAMA Oncol. 2018 Nov 1;4(11):1589-1593. doi: 10.1001/jamaoncol.2018.2297.
2
Identification of Clonal Hematopoiesis Mutations in Solid Tumor Patients Undergoing Unpaired Next-Generation Sequencing Assays.实体瘤患者在接受非配对下一代测序检测时的克隆性造血基因突变的鉴定。
Clin Cancer Res. 2018 Dec 1;24(23):5918-5924. doi: 10.1158/1078-0432.CCR-18-1201. Epub 2018 Jun 4.
3
Detection of clonal hematopoiesis of indeterminate potential in clinical sequencing of solid tumor specimens.实体瘤标本临床测序中不确定潜能克隆性造血的检测
Blood. 2018 May 31;131(22):2501-2505. doi: 10.1182/blood-2018-03-840629. Epub 2018 Apr 20.
4
False-Positive Plasma Genotyping Due to Clonal Hematopoiesis.由于克隆性造血导致的血浆基因分型假阳性。
Clin Cancer Res. 2018 Sep 15;24(18):4437-4443. doi: 10.1158/1078-0432.CCR-18-0143. Epub 2018 Mar 22.
5
Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1β/NLRP3 Inflammasome.Tet2 介导的克隆性造血通过涉及 IL-1β/NLRP3 炎性体的机制加速心力衰竭。
J Am Coll Cardiol. 2018 Feb 27;71(8):875-886. doi: 10.1016/j.jacc.2017.12.037.
6
Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential.细胞应激因素导致不同白血病潜能的造血克隆的扩增。
Nat Commun. 2018 Jan 31;9(1):455. doi: 10.1038/s41467-018-02858-0.
7
Genomic Landscape of Cell-Free DNA in Patients with Colorectal Cancer.结直肠癌患者游离 DNA 的基因组特征
Cancer Discov. 2018 Feb;8(2):164-173. doi: 10.1158/2159-8290.CD-17-1009. Epub 2017 Dec 1.
8
Somatic TP53 variants frequently confound germ-line testing results.体细胞 TP53 变异常使种系检测结果产生混淆。
Genet Med. 2018 Aug;20(8):809-816. doi: 10.1038/gim.2017.196. Epub 2017 Nov 30.
9
Universal Patterns of Selection in Cancer and Somatic Tissues.癌症和体细胞组织中的普遍选择模式。
Cell. 2017 Nov 16;171(5):1029-1041.e21. doi: 10.1016/j.cell.2017.09.042. Epub 2017 Oct 19.
10
Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease.卡那奴单抗治疗动脉粥样硬化疾病的抗炎疗法。
N Engl J Med. 2017 Sep 21;377(12):1119-1131. doi: 10.1056/NEJMoa1707914. Epub 2017 Aug 27.

Managing Clonal Hematopoiesis in Patients With Solid Tumors.

作者信息

Bolton Kelly L, Gillis Nancy K, Coombs Catherine C, Takahashi Koichi, Zehir Ahmet, Bejar Rafael, Garcia-Manero Guillermo, Futreal Andrew, Jensen Brian C, Diaz Luis A, Gupta Dipti, Mantha Simon, Klimek Virginia, Papaemmanuil Elli, Levine Ross, Padron Eric

机构信息

1 Memorial Sloan Kettering Cancer Center, New York, NY.

2 H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.

出版信息

J Clin Oncol. 2019 Jan 1;37(1):7-11. doi: 10.1200/JCO.18.00331. Epub 2018 Nov 7.

DOI:10.1200/JCO.18.00331
PMID:30403571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6354773/
Abstract
摘要