Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 242, 69120 Heidelberg, Germany.
Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 242, 69120 Heidelberg, Germany; Institute of Molecular Immunology and Experimental Oncology, Technical University of Munich, 81675 Munich, Germany.
Cell Metab. 2018 Nov 6;28(5):673-675. doi: 10.1016/j.cmet.2018.10.009.
Fermentation of dietary soluble fibers by our gut microbiota generates short-chain fatty acids (SCFAs) and metabolites, upholding health and being a valuable food supplement. Recently, in Cell, Singh et al. (2018) discovered that fermentable, dietary soluble fibers (e.g., inulin) induced cholestasis and hepatocellular carcinoma (HCC) while improving metabolic dysfunction.
我们的肠道微生物群发酵膳食可溶性纤维会产生短链脂肪酸（SCFAs）和代谢物，维持健康，是一种有价值的食品补充剂。最近，Singh 等人在《细胞》杂志上发现，可发酵的膳食可溶性纤维（如菊粉）在改善代谢功能障碍的同时，会诱导胆汁淤积和肝细胞癌（HCC）。
