Sarkar Sahana, Lai Stanley C S, Lemay Serge G
MESA+ Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands.
Micromachines (Basel). 2016 May 3;7(5):81. doi: 10.3390/mi7050081.
Electrochemistry is ideally suited to serve as a detection mechanism in miniaturized analysis systems. A significant hurdle can, however, be the implementation of reliable micrometer-scale reference electrodes. In this tutorial review, we introduce the principal challenges and discuss the approaches that have been employed to build suitable references. We then discuss several alternative strategies aimed at eliminating the reference electrode altogether, in particular two-electrode electrochemical cells, bipolar electrodes and chronopotentiometry.
电化学非常适合用作小型化分析系统中的检测机制。然而，一个重大障碍可能是可靠的微米级参比电极的实现。在本教程综述中，我们介绍了主要挑战，并讨论了用于构建合适参比电极的方法。然后，我们讨论了几种旨在完全消除参比电极的替代策略，特别是双电极电化学池、双极电极和计时电位法。
