Darke S G, Glasgow M S, Eadie D G
J Cardiovasc Surg (Torino). 1977 Sep-Oct;18(5):471-4.
The incidence of co-existent peptic ulceration in a series of 123 patients with abdominal aortic aneurysms was found to be 26%. Following graft replacement of the aneurysm only one patient suffered complications attributable to peptic ulceration in the form of a small haematemesis. The maximal acid output of nineteen patients was compared to sixteen age-matched controls, and suggested that there was no acid hypersecretion associated with abdominal aneurysms. In view of these findings it was felt that vagotomy and pyloroplasty during the aneurysm repair was not warranted, and that instilling Aludrox down the nasogastric tube in the early-post operative period to reduce the amount of free acid was effective in reducing the incidence of significant complications from pre-existing peptic ulceration or stress ulceration.
在一组123例腹主动脉瘤患者中，同时存在消化性溃疡的发生率为26%。在进行动脉瘤移植置换术后，仅有1例患者出现了因消化性溃疡导致的并发症，表现为少量呕血。将19例患者的最大胃酸分泌量与16例年龄匹配的对照组进行比较，结果表明腹主动脉瘤并无胃酸分泌过多的情况。鉴于这些发现，认为在动脉瘤修复过程中进行迷走神经切断术和幽门成形术并无必要，并且在术后早期经鼻胃管滴注氢氧化铝以减少游离酸量，对于降低既往消化性溃疡或应激性溃疡所致严重并发症的发生率是有效的。
