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斑马鱼信息网:为非编码基因提供新支持,更丰富的基因本体论注释和基因组资源联盟。

The Zebrafish Information Network: new support for non-coding genes, richer Gene Ontology annotations and the Alliance of Genome Resources.

机构信息

The Institute of Neuroscience, University of Oregon, Eugene, OR 97403-1254, USA.

出版信息

Nucleic Acids Res. 2019 Jan 8;47(D1):D867-D873. doi: 10.1093/nar/gky1090.

DOI:10.1093/nar/gky1090
PMID:30407545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6323962/
Abstract

The Zebrafish Information Network (ZFIN) (https://zfin.org/) is the database for the model organism, zebrafish (Danio rerio). ZFIN expertly curates, organizes and provides a wide array of zebrafish genetic and genomic data, including genes, alleles, transgenic lines, gene expression, gene function, mutant phenotypes, orthology, human disease models, nomenclature and reagents. New features at ZFIN include increased support for genomic regions and for non-coding genes, and support for more expressive Gene Ontology annotations. ZFIN has recently taken over maintenance of the zebrafish reference genome sequence as part of the Genome Reference Consortium. ZFIN is also a founding member of the Alliance of Genome Resources, a collaboration of six model organism databases (MODs) and the Gene Ontology Consortium (GO). The recently launched Alliance portal (https://alliancegenome.org) provides a unified, comparative view of MOD, GO, and human data, and facilitates foundational and translational biomedical research.

摘要

斑马鱼信息网络(ZFIN)(https://zfin.org/)是模式生物斑马鱼(Danio rerio)的数据库。ZFIN 专业地整理、组织和提供广泛的斑马鱼遗传和基因组数据,包括基因、等位基因、转基因系、基因表达、基因功能、突变表型、同源物、人类疾病模型、命名法和试剂。ZFIN 的新功能包括增加对基因组区域和非编码基因的支持,以及对更具表现力的基因本体论注释的支持。ZFIN 最近接管了基因组参考序列的维护,作为基因组参考联盟的一部分。ZFIN 也是六个模式生物数据库(MODs)和基因本体论联盟(GO)的联盟基因组资源的创始成员之一。最近推出的联盟门户(https://alliancegenome.org)提供了 MOD、GO 和人类数据的统一、比较视图,并促进了基础和转化医学研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ea9/6323962/75ebf02363bc/gky1090fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ea9/6323962/75ebf02363bc/gky1090fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ea9/6323962/75ebf02363bc/gky1090fig1.jpg

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