原发性甲状腺淀粉样变性一例罕见病例。
A rare case of primary thyroid amyloidosis.
作者信息
Cannizzaro M A, Lo Bianco S, Saliba W, D'Errico S, Pennetti Pennella F, Buttafuoco G, Provenzano D, Magro G
机构信息
Department of Medical and Surgical Sciences and Advanced Technologies, G.F. Ingrassia, Catania, Italy.
Resident in General Surgery Training Program, Department General surgery and medical-surgical specialties, Endocrinesurgery Unit, "Policlinico-Vittorio Emanuele" Hospital, Catania, Italy.
出版信息
Int J Surg Case Rep. 2018;53:179-181. doi: 10.1016/j.ijscr.2018.10.033. Epub 2018 Oct 25.
INTRODUCTION
Amyloid goiter is due to the deposition of amyloid in the thyroid, resulting with enlargement of the gland and compressive symptoms.
CASE
We herein present a case of a 45-year-old male patient who complained of a big swelling in the neck. Ultrasound showed an enlarged thyroid gland with mediastinal involvement. The multinodular appearance was consistent with the diagnosis of multinodular goiter. He had a history of multiple myeloma but no sign of systemic amyloidosis.
DISCUSSION
Thyroid gland was removed and the histopathological examination revealed a diffuse deposition of amyloid associated with metaplastic lipomatosis of the stroma.
CONCLUSIONS
The treatment of choice in patients with amyloid goiter is total thyroidectomy to solve compression symptoms.
引言
淀粉样甲状腺肿是由于淀粉样物质沉积于甲状腺，导致腺体肿大并出现压迫症状。
病例
我们在此报告一例45岁男性患者，其主诉颈部有巨大肿物。超声显示甲状腺肿大并累及纵隔。多结节外观符合多结节性甲状腺肿的诊断。他有多发性骨髓瘤病史，但无系统性淀粉样变性的迹象。
讨论
切除甲状腺，组织病理学检查显示淀粉样物质弥漫性沉积，并伴有间质化生脂肪变性。
结论
淀粉样甲状腺肿患者的首选治疗方法是全甲状腺切除术以解决压迫症状。
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