Alliance for Research in Exercise, Nutrition and Activity, School of Health Sciences, University of South Australia, GPO Box 2471, Adelaide 5001, South Australia.
School of Pharmacy and Medical Sciences, University of South Australia, GPO Box 2471, Adelaide 5001, South Australia.
Nutr Neurosci. 2020 Aug;23(8):646-658. doi: 10.1080/1028415X.2018.1543148. Epub 2018 Nov 8.
The Mediterranean diet has been linked to improved cognitive function and reduced risk of dementia. However, a traditional Mediterranean diet may not meet calcium requirements for older non-Mediterranean populations, which could limit long-term sustainability in Western countries. The current study therefore aimed to determine the cognitive and psychological effects of a Mediterranean diet with adequate calcium for an ageing Australian population. A randomized controlled cross-over design trial compared a Mediterranean diet with 3-4 daily serves of dairy food (MedDairy) with a low-fat (LF) control diet. Forty-one participants aged ≥45 years with systolic blood pressure ≥120 mm Hg and at least two other risk factors for cardiovascular disease completed each dietary intervention for 8 weeks, with an 8-week washout period separating interventions. Attention, processing speed, memory and planning were assessed at the start and end of each intervention using the Cambridge Automated Neuropsychological Test Battery. Mood and health-related quality of life were evaluated using the Profile of Mood States (POMS) and Short-Form Health Survey (SF-36). Dementia risk was also measured using the Framingham Vascular Risk and CAIDE scores. Significant improvements were observed for processing speed ( = .04), Total Mood Disturbance ( = .01), Tension ( = .03), Depression ( = .03), Anger ( = .02), and Confusion ( = .004) following the MedDairy intervention. No significant effects were found for attention, memory and planning, or measures of dementia risk. Our study provides evidence that a Mediterranean diet supplemented with dairy foods may benefit cognitive function and psychological well-being in an ageing population at risk of dementia.
地中海饮食与改善认知功能和降低痴呆风险有关。然而,传统的地中海饮食可能无法满足非地中海老年人群的钙需求,这可能限制了西方国家的长期可持续性。因此,本研究旨在确定一种富含钙的地中海饮食对澳大利亚老龄化人群的认知和心理影响。
一项随机对照交叉设计试验比较了地中海饮食(每天 3-4 份乳制品)和低脂(LF)对照饮食对认知和心理的影响。41 名年龄≥45 岁、收缩压≥120mmHg 且至少有其他两项心血管疾病风险因素的参与者完成了每种饮食干预 8 周,干预之间有 8 周的洗脱期。在每个干预的开始和结束时,使用剑桥自动化神经心理测试电池评估注意力、处理速度、记忆和计划。使用心境状态问卷(POMS)和简明健康调查(SF-36)评估情绪和与健康相关的生活质量。使用弗雷明汉血管风险和 CAIDE 评分测量痴呆风险。
处理速度( = .04)、总情绪困扰( = .01)、紧张( = .03)、抑郁( = .03)、愤怒( = .02)和困惑( = .004)在接受 MedDairy 干预后显著改善。注意力、记忆和计划或痴呆风险的测量指标没有显著影响。
我们的研究提供了证据,表明富含乳制品的地中海饮食可能有益于痴呆风险的老年人群的认知功能和心理健康。