Rothendler J A, Schick E C, Leppo J, Birmingham M J, Green A M, Ryan T J
J Nucl Med. 1987 Sep;28(9):1419-23.
Gated blood-pool scintigraphy (GBPS) is often obtained as the initial test to evaluate symptoms suggestive of left ventricular dysfunction. Since large pericardial effusions may also cause such symptoms, the ability to recognize them on routine GBPS is of clinical importance. Characteristic features of the "halo" sign surrounding the cardiac blood pool were developed, based on the GBPS of patients with known pericardial effusions. These criteria were then applied blindly to 154 consecutive patients who underwent both GBPS and echocardiography. All five patients with large effusions (approximately greater than 500 ml) were correctly identified by GBPS (sensitivity 100%); for patients with moderate effusions (approximately 150-500 ml), the sensitivity was only 33% (3/9). There were three false positives (specificity 98%). We conclude that large pericardial effusions can be identified with high sensitivity and specificity on routine GBPS. Although echocardiography remains the method of choice for the diagnosis of effusions, inspection for characteristics suggesting their presence on GBPS should be part of routine interpretations.
门控心血池闪烁扫描术（GBPS）通常作为评估提示左心室功能障碍症状的初始检查方法。由于大量心包积液也可能导致此类症状，因此在常规GBPS上识别它们的能力具有临床重要性。基于已知心包积液患者的GBPS，发现了围绕心血池的“晕轮”征的特征。然后将这些标准盲目应用于154例连续接受GBPS和超声心动图检查的患者。GBPS正确识别了所有5例大量积液（约大于500毫升）的患者（敏感性100%）；对于中等量积液（约150 - 500毫升）的患者，敏感性仅为33%（3/9）。有3例假阳性（特异性98%）。我们得出结论，在常规GBPS上可以高敏感性和特异性识别大量心包积液。虽然超声心动图仍然是诊断积液的首选方法，但在GBPS上检查提示积液存在的特征应作为常规解读的一部分。
