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是否可以使用低能量方法并避免任何高成本设备从嘉宝果果皮提取物中获得纳米分散体?

Is it possible to obtain nanodispersions with jaboticaba peel's extract using low energy methods and absence of any high cost equipment?

机构信息

Laboratório de Pesquisa, Desenvolvimento e Inovação em Bioprodutos, Universidade Federal de Goiás, Faculdade de Farmácia, Praça Universitária, 1166 - Setor Leste Universitário, CEP: 74605220 Goiânia, GO, Brazil.

Laboratório de Nanobiotecnologia Fitofarmacêutica, Colegiado de Farmácia, Universidade Federal do Amapá, Campus Universitário Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02 Bairro Zerão, CEP: 68902-280 Macapá, AP, Brazil.

出版信息

Food Chem. 2019 Mar 15;276:475-484. doi: 10.1016/j.foodchem.2018.10.037. Epub 2018 Oct 9.

Abstract

Jaboticaba (Myrciaria cauliflora) is considered a "super fruit" due to its remarkable phenolic content and antioxidant capacity. Despite the great potential of its peels, to our knowledge the investigation of novel nanostructured systems with this natural raw material, still considered an industrial residue, is scarce. The present study aimed to obtain nanodispersions with its peel's extract through a low energy method. Antioxidant assays were performed, showing positive results for DPPH (IC = 0.89 μg/mL) and FRAP (225.53 μmol equivalent ferrous sulphate/g). The chemical characterization in terms of flavonoids (2.56%) and total monomeric anthocyanins (0.80%) contents were also performed. Overall, the nanodispersion prepared with the non-ionic surfactant polysorbate 85 and the hydroalcoholic extract standardized in ellagic acid (129 µg/mL) presented the best properties regarding particle size distribution and zeta potential. Thus, it opens perspectives for the generation of novel food-grade nanodispersions through an ecofriendly approach that is in accordance to sustainable concepts.

摘要

嘉宝果(Myrciaria cauliflora)因其显著的酚类含量和抗氧化能力而被视为“超级水果”。尽管其果皮具有巨大的潜力,但据我们所知,利用这种天然原料(仍被视为工业废料)开发新型纳米结构系统的研究还很少。本研究旨在通过低能量方法获得其果皮提取物的纳米分散体。进行了抗氧化测定,DPPH(IC=0.89μg/mL)和FRAP(225.53μmol 当量硫酸亚铁/g)的测定结果均为阳性。还进行了关于类黄酮(2.56%)和总单体花青素(0.80%)含量的化学表征。总的来说,用非离子表面活性剂聚山梨醇酯 85 和以鞣花酸(129μg/mL)为标准的水醇提取物制备的纳米分散体在粒径分布和zeta 电位方面表现出最佳性能。因此,它为通过符合可持续发展理念的环保方法生成新型食品级纳米分散体开辟了前景。

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