脾脏肉芽肿：免疫功能正常宿主中复杂性疾病的罕见表现。
Splenic granulomas: a rare manifestation of complex in an immunocompetent host.
作者信息
Acharya Nupoor, Chattopadhyay Arghya, Sharma Kusum, Sharma Aman
机构信息
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
出版信息
BMJ Case Rep. 2018 Nov 8;2018:bcr-2018-225788. doi: 10.1136/bcr-2018-225788.
Infections caused by complex (MAC) are commonly seen in immunocompromised individuals. Though disseminated MAC infections with splenic granulomas are seen in some patients, MAC infection clinically manifesting as only splenic granulomas is rare. This presentation is even less common in immunocompetent individuals. We report a case of a young adult who presented with fever of unknown origin and was found to have multiple splenic granulomas. Fine needle aspiration cytology and PCR for of the granulomas revealed a diagnosis of MAC infection. The patient was not found to have any immunodeficiency on investigations. This case is perhaps the first case of MAC clinically presenting as splenic granulomas in an immunocompetent individual.
由鸟分枝杆菌复合体（MAC）引起的感染常见于免疫功能低下的个体。虽然在一些患者中可见伴有脾脏肉芽肿的播散性MAC感染，但临床上仅表现为脾脏肉芽肿的MAC感染很少见。这种表现在免疫功能正常的个体中更为罕见。我们报告一例年轻成人病例，该患者因不明原因发热就诊，检查发现有多个脾脏肉芽肿。对肉芽肿进行细针穿刺细胞学检查和PCR检测，结果显示诊断为MAC感染。经检查，该患者未发现任何免疫缺陷。此病例可能是免疫功能正常个体中临床上以脾脏肉芽肿形式出现的首例MAC感染病例。
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