Lobachevskiĭ P N, Krasavin E A, Cherevatenko A P
Radiobiologiia. 1988 May-Jun;28(3):325-30.
The previously developed model was used to study the dependence of radiosensitivity (D0(-1) of Saccharomyces cerevisiae (the wild type and radiosensitive mutant) on linear energy transfer (LET) of ionizing radiation. D0(-1) (L) of haploid yeasts was shown to be associated, to a certain extent, with the capacity of radiation damages repair. As to the wild-type cells, the above function was represented by a curve showing a maximum, while a descending curve was characteristic of the radiosensitive mutant cells deficient in radiation damages repair. The influence of the repair processes on cell radiosensitivity decreased with increasing LET.
先前开发的模型用于研究酿酒酵母（野生型和辐射敏感突变体）的辐射敏感性（D0(-1)）对电离辐射线性能量传递（LET）的依赖性。单倍体酵母的D0(-1)（L）在一定程度上与辐射损伤修复能力相关。对于野生型细胞，上述功能由一条显示最大值的曲线表示，而对于缺乏辐射损伤修复能力的辐射敏感突变体细胞，其特征曲线是下降的。随着LET增加，修复过程对细胞辐射敏感性的影响降低。
