Fortin F, Wallaert B
Département de Pneumologie, Hôpital Calmette, Lille.
Rev Mal Respir. 1988;5(3):275-8.
Pregnancy is an important factor in the outcome of interstitial pneumonias. The outcome for sarcoidosis and rheumatoid disease is favourable as a rule, and these disorders have little influence on the progress of the disease. Idiopathic pulmonary fibrosis or fibrosis complicating scleroderma or dermatopolymyositis requires careful management considering the frequent complications at foetal level. During systemic disorders, recourse to corticosteroid-cyclophosphamide regime is possible from the second trimester. Drug induced pneumonias remain rare, do not influence pregnancy and most often only require the arrest of the incriminated drug.
妊娠是间质性肺炎预后的一个重要因素。结节病和类风湿疾病的预后通常良好,这些疾病对病情进展影响较小。特发性肺纤维化或合并硬皮病或皮肌炎的纤维化,鉴于胎儿层面常见的并发症,需要谨慎处理。在全身性疾病期间,孕中期开始可采用皮质类固醇 - 环磷酰胺疗法。药物性肺炎仍然少见,不影响妊娠,多数情况下仅需停用相关药物。