Negendank W
Department of Medicine, Wayne State University, Detroit, MI 48201.
Scanning Microsc. 1988 Jun;2(2):867-70.
The Symposium of which this paper is a part, "The State Of Water In The Cell", examines evidence which indicates that the bulk water of the cell has physical properties that are different from those of free water in a dilute aqueous solution. The heterogeneity of environments of water within cells makes direct application of physical studies difficult. However, the major physiologic effect of an ordered state of bulk cell water is solute exclusion, and this is also demonstrated by simple polymer solutions. Such systems have provided an opportunity to show that such water has motional correlation times within an order of magnitude of those of free water, and to model other unique properties of bulk cell water.
本文所属的研讨会“细胞中的水状态”,审视了相关证据,这些证据表明细胞中的大量水具有与稀水溶液中自由水不同的物理性质。细胞内水所处环境的异质性使得直接应用物理研究变得困难。然而,细胞大量水有序状态的主要生理效应是溶质排斥,简单聚合物溶液也证明了这一点。这样的系统提供了一个机会来表明这种水具有与自由水运动相关时间在一个数量级内的情况,并对细胞大量水的其他独特性质进行建模。