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15 种连翘属植物叶和花中黄酮类和三萜类成分的色谱特征。

Chromatographic characterization on flavonoids and triterpenes of leaves and flowers of 15 L. species.

机构信息

Department of Technology of Drugs, National University of Pharmacy, Kharkiv, Ukraine.

Department of Pharmaceutical Chemistry, National University of Pharmacy, Kharkiv, Ukraine.

出版信息

Nat Prod Res. 2020 Jan;34(2):317-322. doi: 10.1080/14786419.2018.1528589. Epub 2018 Nov 10.

Abstract

The Hawthorn ( L.) is the most commonly used herb for treating cardiovascular diseases. The purpose of this paper was the analysis and comparison of HPTLC chromatographic profiles of flavonoids and triterpenes of leaves and flowers of 15 L. species occurring throughout Eurasia and North America, and determination of specific distinguishing markers of its fingerprints. The optimal chromatographical conditions for evaluation of flavonoids and triterpenes of 15 Hawthorn species were proposed, the specific HPTLC fingerprints were obtained. The flavonoids fingerprints were qualitatively much the same for the pharmacopoeial species and and other related non-pharmacopoeial European and Asian Hawthorn species including , , , , , , , . The specific distinctive features for Hawthorn species native to North America, including var , , , and , were determined. The evaluation of the triterpenes profiles showed that all 15 analyzed Hawthorn species had quite similar fingerprints.

摘要

山楂(L.)是治疗心血管疾病最常用的草药。本文的目的是分析和比较欧亚大陆和北美的 15 种山楂属植物的叶和花的黄酮类化合物和三萜类化合物的 HPTLC 色谱图谱,并确定其指纹图谱的特定鉴别标志物。提出了评价 15 种山楂属植物黄酮类化合物和三萜类化合物的最佳色谱条件,得到了特定的 HPTLC 指纹图谱。药用山楂属植物和其他相关的非药用欧洲和亚洲山楂属植物,包括 、 、 、 、 、 、 、 ,其黄酮类指纹图谱在质量上非常相似。确定了原产于北美的山楂属植物,包括 、 、 、 和 ,的特有特征。三萜类化合物图谱的评价表明,所有分析的 15 种山楂属植物的指纹图谱非常相似。

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