Jakstas Valdas, Janulis Valdimaras, Labokas Juozas, Bernatoniene Jurga, Brusokas Valdemaras, Malinauskas Faustas, Benetis Raimondas
Department of Pharmaceutical Chemistry and Pharmacognosy, Kaunas University of Medicine, Kaunas, Lithuania.
Medicina (Kaunas). 2003;39 Suppl 2:80-4.
The natural vegetable resources of Republic of Lithuania can be supplied by imported hawthorn species, subspecies and varieties, not growing naturally in the territory of country, but well growing and able to produce the crude drug with local conditions of the climate.
Determinate amounts of phenolic substances (favonoid glycosides and phenolic acids) in the flowers and leaves of collected species of genus Crataegus and Crataegomespilus.
Different examples of crude drug from some Lithuanian regions were extracted with 96% of ethanol and flavonoids were detected spectroscopically and with HPLC (High performance liquid chromatography).
In leaves and flowers were found different quantities of common amounts of flavonoids (1.07-2.53%) and different quantities of individual substances: flavonoids (hyperosid, vitexin-O-rhamnosid, rutin, quercitrin, quercetin, vitexin) and phenolic acids (chlorogenic and caffeic acids).
Flowers and leaves of hawthorn species, introduced in Lithuania, can be used for preparation of crude drugs procurements; the marks of phytochemical compounds of phenotypes from different genetic lines are sufficient grounds for planning of production of crude drug with special phytotherapeutic influences.
立陶宛共和国的天然植物资源可由进口的山楂物种、亚种和变种提供，这些物种在该国境内并非自然生长，但在当地气候条件下生长良好且能够生产粗提药物。
测定收集的山楂属和刺梨属物种的花和叶中酚类物质（黄酮苷和酚酸）的含量。
从立陶宛一些地区采集的不同粗提药物样本用96%乙醇提取，黄酮类化合物通过光谱法和高效液相色谱法（HPLC）进行检测。
在叶和花中发现了不同含量的常见黄酮类化合物（1.07 - 2.53%）以及不同含量的个别物质：黄酮类化合物（金丝桃苷、牡荆素 - O - 鼠李糖苷、芦丁、槲皮苷、槲皮素、牡荆素）和酚酸（绿原酸和咖啡酸）。
引入立陶宛的山楂物种的花和叶可用于制备粗提药物；来自不同遗传系的表型的植物化学化合物特征是规划具有特殊植物治疗作用的粗提药物生产的充分依据。
