Brouillard M Y, Rateau J G
Faculté de Médecine Saint-Antoine, Laboratoire d'Histologie, Paris.
Ann Gastroenterol Hepatol (Paris). 1988 May-Jun;24(3):133-8.
Cholestyramine treatment of new born's infectious diarrhea has been shown to be effective. The study of in vitro binding of bacterial toxins from Vibrio Cholerae and from three strains of Escherichia coli suggest an ionic adsorption of the four toxins to this anion-exchange resin. This immediate binding is effective at the pH of intestinal fluid, therefore the protection of the enterocytes from the biological action of the toxins result of the toxins sequestering effect of the Cholestyramine.
消胆胺治疗新生儿感染性腹泻已被证明是有效的。对霍乱弧菌和三株大肠杆菌产生的细菌毒素的体外结合研究表明,这四种毒素可离子吸附于这种阴离子交换树脂。这种即时结合在肠液的pH值下是有效的,因此,消胆胺对毒素的螯合作用可保护肠上皮细胞免受毒素的生物学作用。