Neuromuscular Diseases Unit of the Department of Neurology, Tel Aviv Sourasky Medical Center, the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Division of Neurology, The Ottawa Hospital and University of Ottawa, Ottawa, Ontario, Canada.
Can J Neurol Sci. 2019 Jan;46(1):79-82. doi: 10.1017/cjn.2018.351. Epub 2018 Nov 13.
Lumbar puncture (LP) performed with the assistance of ultrasound (US) may improve success rate, with fewer puncture attempts and less pain.
To explore the utility of US-assisted LP in a neuromuscular clinic.
We performed a prospective, randomized, open-label study between May 2016 and January 2017. The primary outcome measure was LP success rate, and the secondary outcome measures included procedure time, number of attempts, and the levels of pain, anxiety, and satisfaction.
Lumbar puncture was performed in 40 consecutive patients. Ultrasound-assisted LP had a 100% success rate, compared with 85% (95% confidence interval: 58%-96%) without US assistance, although this difference failed to reach statistical significance. Ultrasound-assisted LP was associated with less pain and, also in patients >60 years of age, with fewer needle insertions. Both groups reported high satisfaction rates, regardless of the use of US.
Ultrasound-assisted LP has a high success rate and less pain than unassisted LP, and can be accomplished easily in the outpatient neuromuscular clinic setting equipped with US.
在超声（US）辅助下进行腰椎穿刺（LP）可以提高成功率，减少穿刺次数，减轻疼痛。
探讨在神经肌肉诊所使用 US 辅助 LP 的效果。
我们于 2016 年 5 月至 2017 年 1 月进行了一项前瞻性、随机、开放标签研究。主要结局指标为 LP 成功率，次要结局指标包括操作时间、尝试次数以及疼痛、焦虑和满意度水平。
连续 40 例患者进行了 LP。US 辅助 LP 的成功率为 100%，而无 US 辅助时为 85%（95%置信区间：58%-96%），但差异无统计学意义。US 辅助 LP 可减轻疼痛，而且对于年龄大于 60 岁的患者，插入的针数也更少。无论是否使用 US，两组的满意度均很高。
US 辅助 LP 的成功率高于无辅助 LP，且疼痛减轻，在配备 US 的门诊神经肌肉诊所环境中易于操作。
