Comprehensive Heart Failure Center and Dept. of Medicine I, University Hospital and University of Würzburg, Germany.
Institute of Clinical Epidemiology and Biometry and Comprehensive Heart Failure Center, University of Würzburg, Germany.
Int J Cardiol. 2019 Jul 1;286:186-189. doi: 10.1016/j.ijcard.2018.10.098. Epub 2018 Oct 30.
About 20% of the German population have a migration background which might influence prevalence of preventable cardiovascular risk factors (CVRF).
We report data of the prospective Characteristics and Course of Heart Failure Stages A-B and Determinants of Progression (STAAB) cohort study investigating a representative sample of inhabitants of the City of Würzburg, Germany, aged 30 to 79 years. Individuals without migration background were defined as follows: German as native language, no other native language, and/or born in Germany. All other participants were defined as individuals with migration background.
Of 2473 subjects (51% female, mean age 54 ± 12 years), 291 (12%) reported a migration background: n = 107 (37%) from a country within the EU, n = 117 (40%) from Russia, and n = 67 (23%) from other countries. Prevalence of hypertension, atherosclerotic disease, and diabetes mellitus was similar in individuals with and without migration background. By contrast, prevalence of obesity and metabolic syndrome was significantly higher in individuals with migration background, with the least favourable profile apparent in individuals from Russia (individuals without vs. with migration background: obesity 19 vs. 24%, p < 0.05; odds ratio: EU: 1.6, Russia: 2.2*, other countries: 0.6; metabolic syndrome 18 vs. 21%, p < 0.05; odds ratio: EU: 1.2, Russia: 1.7*, other countries: 1.5; *p < 0.05).
Individuals with migration background in Germany might exhibit a higher CVRF burden due to a higher prevalence of obesity and metabolic syndrome. Strategies for primary prevention of heart failure may benefit from deliberately considering the migration background.
约 20%的德国人口有移民背景，这可能影响可预防心血管风险因素（CVRF）的患病率。
我们报告了前瞻性心力衰竭 A-B 期特征和进展决定因素（STAAB）队列研究的数据，该研究调查了德国维尔茨堡市具有代表性的 30 至 79 岁居民样本。无移民背景的个体被定义为：母语为德语、没有其他母语且/或出生于德国。所有其他参与者被定义为有移民背景的个体。
在 2473 名受试者中（51%为女性，平均年龄 54±12 岁），291 名（12%）报告有移民背景：来自欧盟国家的有 107 名（37%），来自俄罗斯的有 117 名（40%），来自其他国家的有 67 名（23%）。有和无移民背景的个体中高血压、动脉粥样硬化疾病和糖尿病的患病率相似。相比之下，有移民背景的个体肥胖和代谢综合征的患病率明显更高，来自俄罗斯的个体表现出最不利的特征（无 vs. 有移民背景的个体：肥胖 19% vs. 24%，p<0.05；优势比：欧盟：1.6，俄罗斯：2.2*，其他国家：0.6；代谢综合征 18% vs. 21%，p<0.05；优势比：欧盟：1.2，俄罗斯：1.7*，其他国家：1.5；*p<0.05）。
德国有移民背景的个体可能由于肥胖和代谢综合征的患病率较高，而表现出更高的 CVRF 负担。预防心力衰竭的一级预防策略可能受益于刻意考虑移民背景。
