Young W F, Klee G G
Division of Endocrinology/Metabolism, Mayo Clinic, Rochester, Minnesota.
Endocrinol Metab Clin North Am. 1988 Jun;17(2):367-95.
The regulation of mineralocorticoid secretion and the pathophysiology of primary aldosteronism are reviewed. For conceptual and practical purposes, the diagnostic evaluation of primary aldosteronism is discussed as two series of studies. The first series involves the studies necessary to confirm the diagnosis. The second series of studies guides the therapeutic approach by distinguishing unilateral from bilateral adrenal disease.
本文综述了盐皮质激素分泌的调节及原发性醛固酮增多症的病理生理学。出于概念和实际应用的目的,原发性醛固酮增多症的诊断评估被分为两个系列的研究进行讨论。第一个系列涉及确诊所需的研究。第二个系列的研究通过区分单侧与双侧肾上腺疾病来指导治疗方法。