Yoon Dong Hyun, Tanaka Daiki, Sekiguchi Tetsushi, Shoji Shuichi
Faculty of Science and Engineering, Waseda University, 3-4-1, Okubo, Shinjuku-ku, Tokyo 169-8555, Japan.
Research Organization for Nano & Life Innovation, Waseda University, 513, Tsurumaki-cho, Waseda, Shinjuku-ku, Tokyo 162-0041, Japan.
Micromachines (Basel). 2018 Sep 14;9(9):468. doi: 10.3390/mi9090468.
This paper presents a simple method of droplet formation using liquids that easily wet polydimethylsiloxane (PDMS) surfaces without any surface treatment. Using only structural features and uniform flow focusing, Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) droplets were formed in the full PDMS structure. Extrusion channel and three-dimensional flow focusing resulted in effective fluidic conditions for droplet formation and the droplet size could be precisely controlled by controlling the flow rate of each phase. The proposed structure can be utilized as an important element for droplet based research, as well as a droplet generator.
本文提出了一种简单的液滴形成方法，该方法使用无需任何表面处理就能轻松润湿聚二甲基硅氧烷（PDMS）表面的液体。仅利用结构特征和均匀的流动聚焦，就能在完整的PDMS结构中形成水包油（O/W）和水包油包水（W/O/W）液滴。挤出通道和三维流动聚焦为液滴形成创造了有效的流体条件，并且通过控制各相的流速可以精确控制液滴大小。所提出的结构可作为基于液滴研究的重要元件以及液滴发生器。
