University of Chichester, Institute of Sport, College Lane, PO19 6PE Chichester, UK.
College of Sports Science and Technology, Mahidol University, Salaya, Nakhon Pathom 73170, Thailand.
Nutrients. 2018 Nov 12;10(11):1732. doi: 10.3390/nu10111732.
New Zealand blackcurrant (NZBC) extract affects cardiovascular and metabolic responses during rest and exercise in Caucasian men. Ethnicity and nutritional habits may affect responses to nutritional ergogenic aids. We examined the effects of NZBC extract on cardiovascular, metabolic, and physiological responses during seated rest and moderate-intensity exercise in Southeast Asian men. Seventeen healthy Thai men (age: 22 ± 3 years; body mass index (BMI): 21.8 ± 1.1 kg·m) participated. Resting metabolic equivalent (1-MET) was measured (Oxycon™ mobile, Germany), and an incremental walking protocol was completed to establish the relationship between walking speed and MET. In a double-blind, randomized, placebo-controlled, crossover design, cardiovascular (Physioflow, = 12) and physiological responses (Oxycon, = 17) were measured during both seated rest and a 30-min treadmill walk at five metabolic equivalent (5-MET), with either a seven-day intake of placebo (PL) or two capsules of NZBC extract (each 300 mg capsule contains 35% blackcurrant extract) with a 14-day washout. Paired -tests were used with significance accepted at < 0.05 and a trend for 0.05 > ≤ 0.10. During 30 min of treadmill walking at 5-MET, no differences were observed for heart rate and substrate oxidation. With intake of NZBC during treadmill walking, there was a trend for increased stroke volume by 12% (PL: 83.2 ± 25.1; NZBC: 93.0 ± 24.3 mL; = 0.072) and cardiac output increased by 12% (PL: 9.2 ± 2.6; NZBC: 10.3 ± 2.8 L·min; = 0.057). Systemic vascular resistance decreased by 10% (PL: 779 ± 267; NZBC: 697 ± 245 dyn·s·cm; = 0.048). NZBC extract had no effect on metabolic, physiological, and cardiovascular parameters during seated rest and exercise-induced fat oxidation in Thai men, in contrast to observations in Caucasian men. During treadmill walking, Thai men showed cardiovascular response, indicating vasodilatory effects during moderate-intensity exercise with the intake of NZBC extract. Our findings suggest that the ergogenic responses to anthocyanin intake from New Zealand blackcurrant may be ethnicity-dependent.
新西兰黑加仑（NZBC）提取物影响白种男性静息和运动期间的心血管和代谢反应。种族和营养习惯可能会影响对营养增强剂的反应。我们研究了 NZBC 提取物对东南亚男性静息和中等强度运动期间心血管、代谢和生理反应的影响。17 名健康的泰国男性（年龄：22 ± 3 岁；体重指数（BMI）：21.8 ± 1.1 kg·m）参与了研究。测量静息代谢当量（1-MET）（德国 Oxycon™ mobile），并完成递增步行方案以建立步行速度与 MET 之间的关系。在一项双盲、随机、安慰剂对照、交叉设计中，在静息和 30 分钟跑步机步行（5-MET）期间，使用 Physioflow 测量心血管（ = 12）和生理反应（Oxycon， = 17），并在 7 天内摄入安慰剂（PL）或 NZBC 提取物两胶囊（每个 300mg 胶囊含有 35%黑加仑提取物），洗脱期为 14 天。采用配对检验，显著性水平接受 < 0.05，趋势为 0.05 > ≤ 0.10。在 5-MET 跑步机行走 30 分钟时，心率和底物氧化无差异。在跑步机行走时摄入 NZBC，每搏输出量增加 12%（PL：83.2 ± 25.1；NZBC：93.0 ± 24.3 mL； = 0.072）和心输出量增加 12%（PL：9.2 ± 2.6；NZBC：10.3 ± 2.8 L·min； = 0.057），趋势明显。全身血管阻力降低 10%（PL：779 ± 267；NZBC：697 ± 245 dyn·s·cm； = 0.048）。与白种男性的观察结果相反，新西兰黑加仑提取物在泰国男性静息和运动诱导的脂肪氧化期间对代谢、生理和心血管参数没有影响。在跑步机行走时，泰国男性表现出心血管反应，表明中等强度运动时摄入 NZBC 提取物具有血管扩张作用。我们的研究结果表明，新西兰黑加仑中花青素的摄入对运动表现的有益反应可能取决于种族。
