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来自一名患有镰状细胞贫血的已故供体的成功肝移植病例报告。

Successful Liver Transplantation Case Report from a Deceased Donor with Sickle Cell Anemia.

作者信息

Nacif Lucas Souto, de Mello Estrella Bianca, Pinheiro Rafael Soares, Lima Fabiana Roberto, de Martino Rodrigo Bronze, Andraus Wellington, D'Albuquerque Luiz Carneiro

机构信息

Liver and Gastrointestinal Transplant Division, Department of Gastroenterology, 05403-900 São Paulo, Brazil.

Department of Pathology, University of São Paulo School of Medicine, 05403-900 São Paulo, Brazil.

出版信息

Case Rep Transplant. 2018 Oct 22;2018:5154136. doi: 10.1155/2018/5154136. eCollection 2018.

Abstract

There is a worldwide problem of waiting time and mortality rate associated with remaining on the waiting list for a liver transplant. However, some situations have been encouraging in terms of determining appropriate recipients and expanding the donor criteria. We herein report a case of useful liver donor with sickle cell anemia for liver transplantation. Here we described a case of liver transplantation from a donor with sickle cell anemia to a recipient with hepatocellular carcinoma who was deemed to be at risk of tumor growth and at risk of being dropped from the waiting list. The literature reveals the importance of using safe donors, and we describe the benefits of using a safe, deceased liver donor with sickle cell anemia who was an adequate option for liver transplantation.

摘要

等待肝移植的等待时间和死亡率是一个全球性问题。然而,在确定合适的受者和扩大供体标准方面,有些情况令人鼓舞。我们在此报告一例镰状细胞贫血患者作为有用肝脏供体进行肝移植的病例。我们描述了一例从镰状细胞贫血供体向一名肝细胞癌受者进行肝移植的病例,该受者被认为有肿瘤生长风险且有被从等待名单中剔除的风险。文献揭示了使用安全供体的重要性,我们描述了使用一名安全的、已故的镰状细胞贫血肝脏供体的益处,其是肝移植的一个合适选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c35/6217876/dbf63837df2f/CRIT2018-5154136.001.jpg

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