Izhar Rubina, Husain Samia, Tahir Suhaima, Husain Sonia
Department of Gynaecology And Obstetrics, Abbasi Shaheed Hospital & Karachi Medical and Dental College, Karachi, Pakistan.
Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
J Ultrason. 2018;18(74):186-192. doi: 10.15557/JoU.2018.0028.
To determine the frequency of intrauterine abnormalities in women with unexplained infertility using saline infusion sonography. This was a retrospective cohort study conducted at Aziz medical centre, Karachi, Pakistan between January and December 2015. The study population comprised of women with unexplained infertility who underwent saline infusion sonography as a part of their diagnostic workup. The frequency of uterine abnormalities in these women was determined and the relationship between these pathologies and patient age and body mass index was assessed. Of the 769 women included, 202 (26.3%) had uterine abnormalities. Endometrial polyp (118 cases, 15.3%) was the most common abnormality, followed by submucous fibroids (54, 7%), intrauterine adhesions (20, 2.6%), and septae (10, 5%). Intrauterine pathologies were more common in women with primary infertility (71.8% versus 28.2%, p = 0.002). Uterine abnormalities were most common in the age group 30-34 years ( n = 80, 39.6%) and in overweight patients ( n = 95, 47%). The distribution of abnormalities differed significantly in various age groups ( p = 0.009) and among women with different BMI ( p = 0.029). A significant number of women with unexplained infertility present with unsuspected uterine abnormalities; therefore an assessment of the uterine cavity should be performed in all cases.
使用生理盐水灌注超声检查来确定不明原因不孕症女性子宫内异常的发生率。这是一项回顾性队列研究，于2015年1月至12月在巴基斯坦卡拉奇的阿齐兹医疗中心进行。研究人群包括因不明原因不孕症而接受生理盐水灌注超声检查作为诊断检查一部分的女性。确定这些女性子宫异常的发生率，并评估这些病变与患者年龄和体重指数之间的关系。在纳入的769名女性中，202名（26.3%）有子宫异常。子宫内膜息肉（118例，15.3%）是最常见的异常，其次是黏膜下肌瘤（54例，7%）、宫腔粘连（20例，2.6%）和纵隔（10例，5%）。子宫内病变在原发性不孕症女性中更常见（71.8%对28.2%，p = 0.002）。子宫异常在30 - 34岁年龄组最常见（n = 80，39.6%），在超重患者中也最常见（n = 95，47%）。不同年龄组（p = 0.009）和不同体重指数的女性之间（p = 0.029）异常分布存在显著差异。大量不明原因不孕症女性存在未被怀疑的子宫异常；因此，所有病例均应进行宫腔评估。
