Pragasam Agila Kumari, Veeraraghavan Balaji, Nalini E, Anandan Shalini, Kaye Keith S
Department of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, MI, USA.
Indian J Med Microbiol. 2018 Jul-Sep;36(3):303-316. doi: 10.4103/ijmm.IJMM_18_334.
Infections due to Pseudomonas aeruginosa is a major health concern, especially hospital-acquired infections, in critically ill individuals. Antimicrobial resistance (AMR) increases the morbidity and mortality rates associated with pseudomonal infections. In this review, we aim to address two major aspects of P. aeruginosa. The first part of the review will focus on the burden of AMR and its prevailing mechanisms seen in India, while the second part will focus on the challenges and approaches in the management with special emphasis on the role of newer antimicrobial agents.
铜绿假单胞菌感染是一个主要的健康问题,尤其是在重症患者中的医院获得性感染。抗菌药物耐药性(AMR)增加了与铜绿假单胞菌感染相关的发病率和死亡率。在本综述中,我们旨在探讨铜绿假单胞菌的两个主要方面。综述的第一部分将聚焦于印度抗菌药物耐药性的负担及其常见机制,而第二部分将聚焦于管理中的挑战和方法,特别强调新型抗菌药物的作用。