Ain Tiewsoh Jutang Babat, Khurana Sumeeta, Mewara Abhishek, Sehgal Rakesh, Singh Ankita
Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Med Microbiol. 2018 Jul-Sep;36(3):432-434. doi: 10.4103/ijmm.IJMM_18_259.
Toxocariasis is a neglected soil-transmitted helminthic infection caused by either Toxocara canis or Toxocara cati where humans get infected by accidental ingestion of embryonated eggs, and the definitive hosts are dogs and cats. This study aims to analyse the clinical and laboratory characteristics of Toxocara-infected patients and assessment of response to standard treatment with review of literature. The clinical details of patients with Toxocara serology positive for IgG antibodies by ELISA in 5 years (2013-2017) were retrospectively analysed. A total of 29 patients with clinical features and serology suggestive of Toxocara infection were evaluated. A complete history of 14 patients was available for the analysis. Majority (13/14; 96.5%) of cases were children <15 years, males (79%) and belonged to lower socioeconomic status (64.3%). The most common clinical presentation was fever (78.5%) with respiratory symptoms (57%) followed by gastrointestinal features (35.7%). All the patients had eosinophilia (range 8.3%-85%) and raised total IgE levels. Toxocariasis is more common in children, and the true prevalence may be underestimated. In endemic areas, Toxocara workup should be considered in patients with eosinophilia presenting with respiratory and gastrointestinal features.
弓首蛔虫病是一种被忽视的土源性蠕虫感染，由犬弓首蛔虫或猫弓首蛔虫引起，人类通过意外摄入含胚卵而感染，终末宿主为犬和猫。本研究旨在分析弓首蛔虫感染患者的临床和实验室特征，并通过文献复习评估对标准治疗的反应。对5年（2013 - 2017年）间酶联免疫吸附测定法（ELISA）检测IgG抗体弓首蛔虫血清学阳性患者的临床细节进行回顾性分析。共评估了29例临床特征和血清学提示弓首蛔虫感染的患者。有14例患者的完整病史可供分析。大多数病例（13/14；96.5%）为15岁以下儿童，男性（79%），且社会经济地位较低（64.3%）。最常见的临床表现为发热（78.5%）伴呼吸道症状（57%），其次为胃肠道症状（35.7%）。所有患者均有嗜酸性粒细胞增多（范围8.3% - 85%）及总IgE水平升高。弓首蛔虫病在儿童中更为常见，其实际患病率可能被低估。在流行地区，对于出现呼吸道和胃肠道症状且伴有嗜酸性粒细胞增多的患者，应考虑进行弓首蛔虫检查。
