FPMRS Division, Department of OB/GYN, Montefiore Medical Center, Bronx, New York.
Albert Einstein College of Medicine, Bronx, New York.
Neurourol Urodyn. 2019 Jan;38(1):363-368. doi: 10.1002/nau.23867. Epub 2018 Nov 15.
Opioid abuse is a growing epidemic in the United States, with opioid overdose becoming a leading cause of death. There is wide variation in prescription practices for post-operative opioids due to absence of guidelines. The purpose of this study is to examine postoperative opioid prescribing patterns after urogynecologic surgery and determine usage and management of opioid pills by patients.
This is an observational, prospective study of female patients (N = 143) who underwent urogynecologic (prolapse or incontinence) surgery from June to December 2017 at a single academic center. Patients were surveyed regarding their pain medication use 30 days postoperatively. Survey questions included preoperative pain medication use, quantity of opioid pills consumed, need for additional opioid prescription, and management of remaining pills. T-test and one-way Anova were used for comparison of continuous variables and chi-squared test used for comparison of categorical variables.
Of 143 eligible patients, 99 (69%) responded; 62% of respondent patients underwent vaginal surgery, 22% abdominal surgery with or without vaginal surgery, and 15% underwent other procedures. Postoperatively, 81.8% of patients were prescribed opioids. The average number of tablets prescribed ranged from 12.4 to 17.4 depending on the procedure. 54.3% of patients reported using less than half of their prescribed opioid prescription. Of the patients who had excess opioid tablets, only 8.6% reported discarding their opioids.
To date, no guidelines exist on prescribing opioids postoperatively. Opioids are overprescribed post-operatively with over half of patients using less than half of the opioids prescribed to them.
阿片类药物滥用在美国是一个日益严重的问题,阿片类药物过量已成为主要死因。由于缺乏指南,术后阿片类药物的处方实践存在广泛差异。本研究旨在检查妇科泌尿手术术后阿片类药物的处方模式,并确定患者对阿片类药物的使用和管理。
这是一项观察性、前瞻性研究,纳入了 2017 年 6 月至 12 月在一家学术中心接受妇科泌尿(脱垂或尿失禁)手术的 143 名女性患者。术后 30 天对患者进行疼痛药物使用情况调查。调查问题包括术前疼痛药物使用情况、阿片类药物片数、是否需要额外的阿片类药物处方以及剩余药物的管理。采用 t 检验和单因素方差分析比较连续变量,采用卡方检验比较分类变量。
在 143 名符合条件的患者中,有 99 名(69%)患者做出回应;62%的应答患者接受了阴道手术,22%的患者接受了腹部手术(伴有或不伴有阴道手术),15%的患者接受了其他手术。术后,81.8%的患者开了阿片类药物。根据手术类型,开的片剂数量平均为 12.4 至 17.4 片。54.3%的患者报告使用了不到一半的处方阿片类药物。在有多余阿片类药物片剂的患者中,只有 8.6%的患者报告丢弃了他们的阿片类药物。
迄今为止,尚无术后开具阿片类药物的指南。术后阿片类药物过度开具,超过一半的患者使用的阿片类药物不到处方量的一半。