Molino de la Vega Health Center, Huelva, Spain.
La Orden Health Center, Huelva, Spain.
Curr Med Res Opin. 2019 Jan;35(1):167-173. doi: 10.1080/03007995.2018.1549026. Epub 2018 Dec 5.
Digital interventions, such as smartphone applications (apps), are becoming an increasingly common way to support medication adherence and self-management in chronic illness. To evaluate the effectiveness of the intervention in pharmacological therapeutic adherence in mild to moderate arterial hypertension (AHT), through an app installed on a mobile phone, as well as the degree of control reached by the patient with this tool. Prospective, randomized controlled trial, full study and multicenter study. Four primary care centers participated. One hundred and fifty-four hypertensive patients under antihypertensive treatment were included. Two groups were established: a control group (CG) with usual intervention ( = 77) and an intervention group ( = 77) (IG), targeting hypertensive people who owned and regularly used a mobile smartphone, specifically using the app called AlerHTA to promote health education and reminder of appointments. There were three visits: initial, 6 and 12 months. Drug adherence was measured by electronic monitors (MEMSs). The primary outcomes were average daily percentage adherence between 80 and 100%, and AHT control. A total of 148 patients finished the study. Mean age was 57.5 ± 9.9. Global adherence was 77.02% (CI = 70.25-83.79) and daily adherence was 74.32% (CI = 67.29-81.35%). Daily adherence was 93.15% and 86.3% in IG, and 70.66% and 62.66% in CG after 6 and 12 months respectively ( < .05). The percentage of uncontrolled patients was 28.3% (CI = 21.05-35.55%). The control of high blood pressure at 12 months was 17.8% and 38.6% for IG and CG respectively ( < .05). The number of patients needed to treat to avoid non-adherence (NNT) was 4.23 patients. The intervention with an app installed on the mobile phones of hypertensive patients favors pharmacological therapeutic adherence and improves the percentage of hypertensive patient control. Spanish Agency of Medicine: EPA-SP UN-HTA-2015-01.
数字干预措施，如智能手机应用程序（apps），正在成为支持慢性病患者药物依从性和自我管理的一种越来越常见的方法。通过在手机上安装应用程序来评估干预措施在轻度至中度动脉高血压（AHT）中的药物治疗依从性的有效性，以及患者使用该工具达到的控制程度。前瞻性、随机对照试验，完整研究和多中心研究。有四个初级保健中心参与。共纳入 154 名正在接受降压治疗的高血压患者。建立了两组：对照组（CG）接受常规干预（n=77）和干预组（IG）（n=77），针对拥有并经常使用智能手机的高血压人群，特别是使用名为 AlerHTA 的应用程序来促进健康教育和提醒预约。共进行了三次访视：初始访视、6 个月和 12 个月。药物依从性通过电子监测器（MEMS）测量。主要结局是 80%至 100%的平均每日百分比依从率和 AHT 控制率。共有 148 名患者完成了研究。平均年龄为 57.5±9.9 岁。总体依从率为 77.02%（CI=70.25-83.79），每日依从率为 74.32%（CI=67.29-81.35%）。IG 组的每日依从率分别为 93.15%和 86.3%，CG 组分别为 70.66%和 62.66%，6 个月和 12 个月后（<.05）。未控制患者的百分比为 28.3%（CI=21.05-35.55%）。IG 和 CG 组的 12 个月高血压控制率分别为 17.8%和 38.6%（<.05）。避免不依从（NNT）的患者人数为 4.23 人。在高血压患者的手机上安装应用程序的干预措施有利于药物治疗依从性，并提高高血压患者的控制率。西班牙药品管理局：EPA-SP UN-HTA-2015-01。
