Yokozawa T
Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Nihon Geka Gakkai Zasshi. 1988 Apr;89(4):582-94.
Preoperative ultrasonographic findings of thyroid carcinoma were analysed in terms of their correlation with pathological features on the cut surface of surgically removed specimens, and the results were found to facilitate correct diagnosis. For this study, 414 patients with thyroid tumors, consisting of 172 with carcinomas and 242 with benign tumors, were examined by a 7.5 MHz high-resolutional real-time ultrasonography. Sonographic criteria for diagnosing thyroid carcinoma were newly proposed in this study. They were divided into major and minor criteria: The former were findings frequently observed in carcinoma, and the latter were findings observed in benign tumors but, rarely, in carcinoma also. By applying these criteria in thyroid patients, papillary carcinoma was diagnosed more correctly than follicular carcinoma, and solid carcinoma was more easily diagnosed than cystic carcinoma. Microcarcinomas, less than 10mm in maximum diameter, were frequently diagnosed by ultrasonography; 20 out of 36 were detected by these criteria. Intraglandular dissemination was also detected in 22 out of 87. From these studies, it was clear that the accuracy of ultrasonographic diagnosis for microcarcinoma and intraglandular dissemination was closely related to the size of the tumor. The diagnostic limitation was a maximum tumor diameter of 5mm. The superiority of ultrasonography to other diagnostic methods was also discussed.
对甲状腺癌术前超声检查结果与手术切除标本切面病理特征的相关性进行分析,结果发现有助于正确诊断。在本研究中,414例甲状腺肿瘤患者接受了7.5MHz高分辨率实时超声检查,其中172例为癌,242例为良性肿瘤。本研究新提出了诊断甲状腺癌的超声标准。这些标准分为主要标准和次要标准:前者是在癌中经常观察到的表现,后者是在良性肿瘤中观察到但在癌中很少见的表现。通过将这些标准应用于甲状腺患者,乳头状癌比滤泡状癌诊断更准确,实性癌比囊性癌更容易诊断。最大直径小于10mm的微小癌经常通过超声检查诊断出来;36例中有20例通过这些标准检测到。87例中有22例也检测到腺内播散。从这些研究中可以清楚地看出,超声诊断微小癌和腺内播散的准确性与肿瘤大小密切相关。诊断的局限性是肿瘤最大直径为5mm。还讨论了超声检查相对于其他诊断方法的优越性。