Koza K D, Wengors H, Gerlach K, Spörl E, Matthäus W
Abteilung für Kryomedizin, Technischen Universität Dresden, Sektion Energieumwandlung.
Z Exp Chir Transplant Kunstliche Organe. 1988;21(3):163-72.
The knowledge of the depth of infiltration of the freezing front in the treated tissue represented an essential demand for an optimal cryotherapy (sprayfreezing and contactfreezing). The hitherto used invasive measuring methods are connected with a tissue traumatisation and therefore only applicable in a limited way. On that account the non-invasive ultrasound-A-picture-technique was applied for defining the freezing front extension. Its qualification was represented in vitro (gelatin), in living biological tissue (muscle of rabbit), and on the human eye (cryotherapy of the primary glaucoma). The use of the sonography in the cryotherapy can be recommended for other special medical branches too.
了解治疗组织中冷冻前沿的浸润深度是实现最佳冷冻疗法（喷雾冷冻和接触冷冻）的一项基本要求。迄今为止使用的侵入性测量方法会造成组织创伤，因此应用有限。基于此，采用了非侵入性超声A成像技术来确定冷冻前沿的范围。其验证在体外（明胶）、活体生物组织（兔肌肉）以及人眼（原发性青光眼冷冻治疗）中进行。超声检查在冷冻疗法中的应用也可推荐给其他特殊医学分支。
