[Lichen ruber ulcerosus. Differentiation from Graham-Little syndrome. Pathogenesis and therapy].

A 61-year-old female patient having suffered for several years from typical Graham-Little's syndrome developed lichen ulcerosus after a period of 9 years. We discuss the relationship between these clinical manifestations with special reference to the pathogenesis and distribution of skin lesions in lichen rubber ulcerosus. Among the numerous therapeutic approaches, treatment with chloroquine or dapsone as well as skin grafting seem to be most promising.