Behavioural Science Institute, Radboud University, The Netherlands.
Behavioural Science Institute, Radboud University, The Netherlands.
J Affect Disord. 2019 Feb 15;245:297-304. doi: 10.1016/j.jad.2018.11.042. Epub 2018 Nov 5.
Depression is highly comorbid and depressive symptoms are very common. Symptom severity adversely affects treatment outcome and later health status. Established interventions for depression leave ample room for improvement. Short interventions that target specific vulnerabilities emerge as plausible augmentation strategies. In this study, we tested the efficacy of a computerized general positivity-approach training and its effect on depressive symptoms.
Patients (N = 240) with various diagnoses of mental disorders who received treatment-as-usual in an inpatient setting were randomly assigned to also receive either 4 sessions of a positivity-approach training or 4 sessions of sham training. Depression severity was assessed at baseline and post-treatment. Training data were analyzed for a subset of 111 patients.
Depressive symptoms were reduced more after positivity-approach training than after sham training. Initial depression symptom severity moderated the intervention effects, such that approach tendencies and depression symptoms were only affected positively among patients with higher levels of initial depression symptom severity.
The findings provide preliminary support for positivity-approach training as an add-on treatment option for depressive symptoms.
抑郁症高度共病，抑郁症状非常常见。症状严重程度会对治疗效果和后期健康状况产生不利影响。现有的抑郁症干预措施仍有很大的改进空间。针对特定脆弱性的短期干预措施可能成为合理的增效策略。本研究旨在测试一种计算机化的一般性积极方法训练的疗效及其对抑郁症状的影响。
在住院环境中接受常规治疗的患有各种精神障碍诊断的患者（N=240）被随机分配接受 4 次积极方法训练或 4 次假训练。在基线和治疗后评估抑郁严重程度。对 111 名患者的亚组进行了训练数据分析。
积极方法训练后抑郁症状的减轻程度大于假训练。初始抑郁症状严重程度调节了干预效果，即只有在初始抑郁症状严重程度较高的患者中，积极倾向和抑郁症状才会受到积极影响。
这些发现为积极方法训练作为抑郁症状的附加治疗选择提供了初步支持。
