Thermal and Mountain Medicine Division, U.S. Army Research Institute of Environmental Medicine, Natick, MA.
Med Sci Sports Exerc. 2019 Apr;51(4):744-750. doi: 10.1249/MSS.0000000000001843.
To determine the efficacy residing for 2 d at various altitudes while sedentary (S) or active (A; ~90 min hiking 2 d) on exercise performance at 4300 m.
Sea-level (SL) resident men (n = 45) and women (n = 21) (mean ± SD; 23 ± 5 yr; 173 ± 9 cm; 73 ± 12 kg; V˙O2peak = 49 ± 7 mL·kg·min) were randomly assigned to a residence group and, S or A within each group: 2500 m (n = 11S, 8A), 3000 m (n = 6S, 12A), 3500 m (n = 6S, 8A), or 4300 m (n = 7S, 8A). Exercise assessments occurred at SL and 4300 m after 2-d residence and consisted of 20 min of steady-state (SS) treadmill walking (45% ± 3% SL V˙O2peak) and a 5-mile, self-paced running time trial (TT). Arterial oxygen saturation (SpO2) and HR were recorded throughout exercise. Resting SpO2 was recorded at SL, at 4 and 46 h of residence, and at 4300 m before exercise assessment. To determine if 2-d altitude residence improved 4300 m TT performance, results were compared with estimated performances using a validated prediction model.
For all groups, resting SpO2 was reduced (P < 0.01) after 4 h of residence relative to SL inversely to the elevation and did not improve after 46 h. Resting SpO2 (~83%) did not differ among groups at 4300 m. Although SL and 4300 m SS exercise SpO2 (97% ± 2% to 74% ± 4%), HR (123 ± 10 bpm to 140 ± 12 bpm) and TT duration (51 ± 9 to 73 ± 16 min) were different (P < 0.01), responses at 4300 m were similar among all groups, as was actual and predicted 4300 m TT performances (74 ± 12 min).
Residing for 2 d at 2500 to 4300 m, with or without daily activity, did not improve resting SpO2, SS exercise responses, or TT performance at 4300 m.
在不同海拔高度 sedentary(S)或 active(A;~90 分钟徒步旅行 2 天)2 天后,确定在 4300 米海拔高度进行运动表现的疗效。
海平面(SL)居民男性(n=45)和女性(n=21)(平均值±标准差;23±5 岁;173±9 厘米;73±12 千克;V˙O2peak=49±7 mL·kg·min)被随机分配到一个居住组,并在每个组内进行 S 或 A:2500 米(n=11S,8A)、3000 米(n=6S,12A)、3500 米(n=6S,8A)或 4300 米(n=7S,8A)。在 2 天居住后,在 SL 和 4300 米处进行运动评估,包括 20 分钟稳态(SS)跑步机步行(45%±3%SL V˙O2peak)和 5 英里,自我计时跑步时间试验(TT)。在整个运动过程中记录动脉血氧饱和度(SpO2)和心率。在 SL、居住 4 小时和 46 小时以及在运动评估前在 4300 米处记录静息 SpO2。为了确定 2 天的海拔居住是否改善了 4300 米 TT 表现,使用验证的预测模型比较了结果与估计表现。
对于所有组,与 SL 相比,居住 4 小时后静息 SpO2降低(P<0.01),与海拔呈反比,而在 46 小时后没有改善。在 4300 米处,各组之间的静息 SpO2没有差异。尽管 SL 和 4300 米 SS 运动 SpO2(97%±2%至 74%±4%)、心率(123±10 bpm 至 140±12 bpm)和 TT 持续时间(51±9 至 73±16 分钟)不同(P<0.01),但所有组在 4300 米处的反应相似,实际和预测的 4300 米 TT 表现也相似(74±12 分钟)。
在 2500 至 4300 米海拔居住 2 天,无论有无日常活动,都不能改善静息 SpO2、SS 运动反应或 4300 米 TT 表现。