Bao Shi-Chun, Wong Wan-Wa, Leung Thomas Wh, Tong Kai-Yu
Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:247-250. doi: 10.1109/EMBC.2018.8512208.
Brain oscillation and motor control process would change due to chronic stroke. Inter-hemisphere brain activation patterns may relate to motor related recovery. This study employed cortico-muscular coherence to explore cortical motor control process during wrist isometric contraction experiments of both affected and unaffected hands from chronic stroke subjects. Eleven chronic stroke subjects with moderate hand function involved in the experiments and each subject took three visits. Multitaper coherence estimation with bias-correction was performed to acquire cortico-muscular coherence, neuronal coherence source Localization was conducted to determine typical scalp motivation area during isometric contraction. Non-parametric permutation based multiple frequency bin statistics was utilized to compare the difference between two sides. The results demonstrated significant typical low gamma band inter-hemisphere disparity in cortico-muscular coherence between two sides after chronic stroke. The spatial topographical pattern and source Localization outcomes also supported these findings.
慢性中风会导致脑振荡和运动控制过程发生变化。半球间脑激活模式可能与运动相关恢复有关。本研究采用皮质-肌肉相干性来探索慢性中风患者患侧和未患侧手在手腕等长收缩实验期间的皮质运动控制过程。11名手部功能中度的慢性中风患者参与了实验，每位患者进行了三次就诊。采用具有偏差校正的多窗谱相干估计来获取皮质-肌肉相干性，进行神经元相干源定位以确定等长收缩期间典型的头皮兴奋区域。利用基于非参数置换的多频率区间统计来比较两侧之间的差异。结果表明，慢性中风后两侧皮质-肌肉相干性在典型的低伽马波段存在显著的半球间差异。空间地形模式和源定位结果也支持了这些发现。
