Abukhalaf Zaid, Javan-Khoshkholgh Amir, Alrofati Wahib, Farajidavar Aydin
Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:4178-4181. doi: 10.1109/EMBC.2018.8513369.
We have designed and developed a configurable system that can generate and deliver a variety of electrical pulses suitable for gastrointestinal studies. The system is composed of a front-end unit, and a back-end unit that is connected to a computer. The front-end unit contains a stimulating module with 32 channels configured to generate two different current pulses, simultaneously. Commercial off-the-shelf components were used to develop front- and back-end units. A graphical user interface was designed in LabVIEW that allows configuration of the stimulation pulses through the back-end unit in real-time. The system was successfully validated on bench top. The bench-top studies showed the capability of the system to deliver bipolar, monopolar and unbalanced electrical pulses to a maximum load of 1.5 kΩ, at amplitudes up to ±10 mA with resolution of 10 μA, and pulse widths varying between 80 μs to 60 s with the resolution of 80 μs. This study reports the first multi-channel bipolar stimulator that is designed for gastrointestinal studies, and can be configured wirelessly. The system can be used for treating functional gastrointestinal disorders in future.
我们设计并开发了一种可配置系统,该系统能够生成并输送适合胃肠研究的各种电脉冲。该系统由一个前端单元和一个连接到计算机的后端单元组成。前端单元包含一个具有32个通道的刺激模块,配置为可同时生成两种不同的电流脉冲。前端和后端单元的开发采用了商用现货组件。在LabVIEW中设计了一个图形用户界面,可通过后端单元实时配置刺激脉冲。该系统在台式设备上成功得到验证。台式研究表明,该系统能够向最大负载为1.5 kΩ输送双极、单极和不平衡电脉冲,幅度高达±10 mA,分辨率为10 μA,脉冲宽度在80 μs至60 s之间变化,分辨率为80 μs。本研究报告了首个专为胃肠研究设计且可无线配置的多通道双极刺激器。该系统未来可用于治疗功能性胃肠疾病。